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IgM and its receptors and binding proteins / Hiromi Kubagawa, Peter D. Burrows, editors.

Contributor(s): Burrows, Peter D.,, editor literario | Kubagawa, Hiromi,, editor literario
Material type: materialTypeLabelE-bookSeries: (Current topics in microbiology and immunology ; v. 408).Publisher: Cham, Switzerland : Springer International Publishing, 2017Copyright date: 2017Description: 1 recurso en línea : ilustraciones.ISBN: 3319645242; 3319645269; 9783319645247; 9783319645261.Subject: InmunoglobulinasOnline resources: Acceso a este recurso digital (usuarios Universidad Europea de Madrid)Digital Resources
Contents:
""Preface""; ""References""; ""Contents""; ""22 The Appearance and Diversification of Receptors for IgM During Vertebrate Evolution""; ""Abstract""; ""1 The Adaptive Immune System of Vertebrates""; ""2 The Appearance of Receptors Interacting with the Constant Domain of Igs""; ""3 The Polymeric Ig Receptorâ#x80;#x94;PIGR""; ""4 The FcαµR""; ""5 The FcµR""; ""6 Concluding Remarks""; ""Acknowledgements""; ""References""; ""23 Authentic IgM Fc Receptor (FcμR)""; ""Abstract""; ""1 Introduction""; ""2 Lymphocyte-Restricted Expression of FcµR""; ""3 Unique Ligand-Binding Activity""
""1 Introduction""""1.1 IgG-Mediated Feedback Suppression""; ""1.2 IgG-Mediated Feedback Enhancement""; ""1.3 IgE-Mediated Feedback Enhancement""; ""1.4 IgM-Mediated Feedback Enhancement""; ""2 Basic Parameters of IgM-Mediated Enhancement""; ""2.1 Antigens""; ""2.2 The IgM Molecule and Mode of Administration""; ""2.3 Primary Antibody Responses""; ""2.4 Priming for Memory Responses""; ""2.5 Avidity of the Enhanced Response""; ""2.6 Germinal Center Responses""; ""2.7 Specificity of the Enhanced Antibody Response""; ""2.8 T Cells and IgM-Mediated Enhancement""
""3 Complement in Antibody Responses to Uncomplexed Antigen""""4 Complement in Antibody Responses to IgM-Antigen Complexes""; ""4.1 Complement Activation by IgM""; ""4.2 Complement Receptors 1 and 2, CR1/2, in Antibody Responses to IgM-Antigen Complexes""; ""4.3 Cμ13 Knock-in Mice with a Point Mutation in the IgM Heavy Chain Abolishing C1q-Binding""; ""4.4 FcμR (Toso/Faim3) and IgM-Mediated Enhancement""; ""4.5 Other IgM-Binding Receptors and IgM-Mediated Enhancement""; ""4.6 Specific IgM from Wildtype but not Cμ13 Mice, Causes Rapid Deposition of C3 on SRBC in Vivo""
""3.1 Fcµ-Specificity, Ligand-Binding Avidity, and Glycosylation""""3.2 Cis Engagement""; ""3.3 Modulatory Effect of FcµR by Cis Engagement""; ""3.4 Key Residues in the Transmembrane and Cytoplasmic Tail for FcµR Function""; ""4 FcµR Deficiency in Mice""; ""5 Epilogue""; ""Acknowledgements""; ""References""; ""40 FCRLAâ#x80;#x94;A Resident Endoplasmic Reticulum Protein that Associates with Multiple Immunoglobulin Isotypes in B Lineage Cells""; ""Abstract""; ""1 Introductionâ#x80;#x94;Fc Receptors and Their Relatives""; ""2 The Identification of FCRLA and FCRLB""; ""3 The FCRLA Genome Landscape""
""4 Features of the FCRLA Protein""""5 FCRLAâ#x80;#x94;Phylogeny and Disease Association""; ""6 FCRLAâ#x80;#x94;Expression Pattern and Regulation""; ""7 FCRLA is a Soluble Resident ER Protein""; ""8 FCRLA is Retained in the ER via its N-terminal Disordered Domain""; ""9 FCRLA Associates with Multiple Ig Isotypes in the ER""; ""10 TRIM21â#x80;#x94;One Other Intracellular Fc Receptor that Binds Multiple Ig Isotypes""; ""11 FCRLA Functionâ#x80;#x94;Facts and Speculations""; ""11.1 Facts""; ""11.2 Speculations""; ""Acknowledgements""; ""References""; ""24 Specific IgM and Regulation of Antibody Responses""; ""Abstract""
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Holdings
Item type Current library Collection Call number Status Date due Barcode Item holds
LIBRO-E NO PRÉSTAMO LIBRO-E NO PRÉSTAMO Madrid Digital Acceso Electrónico (UEM) Ciencias de la Salud QR186.8.M2 2017 EB (Browse shelf(Opens below)) Acceso electrónico eBook.20024239
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Springer Biomedical and Life Sciences eBooks 2017 English+International

Incluye referencias bibliográficas

880-01 ""Preface""; ""References""; ""Contents""; ""22 The Appearance and Diversification of Receptors for IgM During Vertebrate Evolution""; ""Abstract""; ""1 The Adaptive Immune System of Vertebrates""; ""2 The Appearance of Receptors Interacting with the Constant Domain of Igs""; ""3 The Polymeric Ig Receptorâ#x80;#x94;PIGR""; ""4 The FcαµR""; ""5 The FcµR""; ""6 Concluding Remarks""; ""Acknowledgements""; ""References""; ""23 Authentic IgM Fc Receptor (FcμR)""; ""Abstract""; ""1 Introduction""; ""2 Lymphocyte-Restricted Expression of FcµR""; ""3 Unique Ligand-Binding Activity""

""1 Introduction""""1.1 IgG-Mediated Feedback Suppression""; ""1.2 IgG-Mediated Feedback Enhancement""; ""1.3 IgE-Mediated Feedback Enhancement""; ""1.4 IgM-Mediated Feedback Enhancement""; ""2 Basic Parameters of IgM-Mediated Enhancement""; ""2.1 Antigens""; ""2.2 The IgM Molecule and Mode of Administration""; ""2.3 Primary Antibody Responses""; ""2.4 Priming for Memory Responses""; ""2.5 Avidity of the Enhanced Response""; ""2.6 Germinal Center Responses""; ""2.7 Specificity of the Enhanced Antibody Response""; ""2.8 T Cells and IgM-Mediated Enhancement""

""3 Complement in Antibody Responses to Uncomplexed Antigen""""4 Complement in Antibody Responses to IgM-Antigen Complexes""; ""4.1 Complement Activation by IgM""; ""4.2 Complement Receptors 1 and 2, CR1/2, in Antibody Responses to IgM-Antigen Complexes""; ""4.3 Cμ13 Knock-in Mice with a Point Mutation in the IgM Heavy Chain Abolishing C1q-Binding""; ""4.4 FcμR (Toso/Faim3) and IgM-Mediated Enhancement""; ""4.5 Other IgM-Binding Receptors and IgM-Mediated Enhancement""; ""4.6 Specific IgM from Wildtype but not Cμ13 Mice, Causes Rapid Deposition of C3 on SRBC in Vivo""

""3.1 Fcµ-Specificity, Ligand-Binding Avidity, and Glycosylation""""3.2 Cis Engagement""; ""3.3 Modulatory Effect of FcµR by Cis Engagement""; ""3.4 Key Residues in the Transmembrane and Cytoplasmic Tail for FcµR Function""; ""4 FcµR Deficiency in Mice""; ""5 Epilogue""; ""Acknowledgements""; ""References""; ""40 FCRLAâ#x80;#x94;A Resident Endoplasmic Reticulum Protein that Associates with Multiple Immunoglobulin Isotypes in B Lineage Cells""; ""Abstract""; ""1 Introductionâ#x80;#x94;Fc Receptors and Their Relatives""; ""2 The Identification of FCRLA and FCRLB""; ""3 The FCRLA Genome Landscape""

""4 Features of the FCRLA Protein""""5 FCRLAâ#x80;#x94;Phylogeny and Disease Association""; ""6 FCRLAâ#x80;#x94;Expression Pattern and Regulation""; ""7 FCRLA is a Soluble Resident ER Protein""; ""8 FCRLA is Retained in the ER via its N-terminal Disordered Domain""; ""9 FCRLA Associates with Multiple Ig Isotypes in the ER""; ""10 TRIM21â#x80;#x94;One Other Intracellular Fc Receptor that Binds Multiple Ig Isotypes""; ""11 FCRLA Functionâ#x80;#x94;Facts and Speculations""; ""11.1 Facts""; ""11.2 Speculations""; ""Acknowledgements""; ""References""; ""24 Specific IgM and Regulation of Antibody Responses""; ""Abstract""

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