Foreword; Preface; Contents; Editors and Contributors; Contributors; 1 Making a Diagnosis; Introduction; The Initial Assessment; Semen Analysis; Advanced Semen Studies; Oxidative Stress; Sperm DNA Fragmentation; Sperm Viability; Anti-sperm Antibody (ASA) Testing; Post-ejaculatory Urinalysis; Hormonal Evaluation; Genetic Testing; Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene; Ultrasonography; Scrotal Ultrasonography; Transrectal Ultrasonography; Vasography; Magnetic Resonance Imaging; Pelvic Imaging; Pituitary Gland Imaging; Conclusion; References.

2 Interpreting Semen Analysis and Level 2 Sperm TestingIntroduction; The Reliability of Semen Analysis Result; Standardization of Semen Analysis Techniques; Biological Variability; External Technical Factors that May Influence Semen Analysis Result; Does the Traditional Semen Analysis Identify a Specific Pathology?; The Significance of Semen Volume; The Significance of Semen pH; The Value of Semen Analysis in Azoospermic Cases; Can This Man Achieve a Pregnancy Given His Female Partner's Fertility Potential?; Level 2 Sperm Testing; References.

3 Medical and Lifestyle Approaches to Improving Semen QualityClinical Vignette; Lifestyle Approaches to Improving Semen Quality; Smoking; Alcohol; Exogenous Testosterone and Anabolic Steroids Abuse; Medical Approaches to Improving Semen Quality; Selective Estrogen Receptor Modulators; Aromatase Inhibitors; Gonadotropins; Conclusion; References; 4 Testosterone and Anabolic Steroid Abuse; Introduction; Biophysiology of Testosterone; Synthesis; Transport; Metabolism; Regulation of Testosterone Production; Hypothalamic Pituitary Gonadal Axis; Paracrine Regulation of Testosterone Production.

Male Infertility ManagementSelective Estrogen Receptor Modulators; Human Chorionic Gonadotropin; Human Chorionic Gonadotropin and Testosterone; Aromatase Inhibitors (Anastrozole and Letrozole); Sexual Dysfunction Management; Conclusion; References; 5 Managing Infertility Due to Endocrine Causes; Introduction; Case Report; Male Hypogonadism; Hyperprolactinemia; Thyroid Diseases; Obesity and Metabolic Syndrome; Evaluation of an Infertile Man from an Endocrinological Point of View; Therapy; Treatment of Male Hypogonadism; Hormonal Treatment of Idiopathic Infertility.

Physiological Functions of TestosteroneWhat Are the "Anabolic Steroids"?; Testosterone and Anabolic Steroids Abuse; Nonmedical (Athletic) AAS Abuse; Clinical Case Scenario 1; The Therapeutic Use of Testosterone; Clinical Case Scenario 2; Effects of Testosterone and Anabolic Steroid Abuse; Effects on Male Fertility; Effect on Sexual Function; Other Effects of Testosterone and Anabolic Steroid Abuse; Cardiovascular Effects; Hepatic; Musculoskeletal; Subcutaneous Tissue; Neuropsychiatric; Diagnosis of Testosterone and Anabolic Steroid Abuse; Management of Testosterone and Anabolic Steroid Abuse.

This case-based guide is written from the clinician's perspective, dealing with a defined male infertility problem, tracing the actual clinical pathway arriving at the diagnosis, and discussing the treatment options and the likely outcome. Rather than focusing on excessive theoretical details, each chapter presents a unique clinical vignette or scenario, the relevant aspects of which are followed throughout the entire chapter, correlating specific fertility issues with clinical findings, describing treatment options, prognoses and procedures (when indicated), and concluding with practical clinical pearls. Opening with chapters describing current diagnoses of male infertility and semen analysis, the subsequent cases presented cover a variety of relevant topics in male infertility, including anabolic steroid use, ejaculatory and erectile dysfunction, azoospermia, Klinefelter Syndrome, varicocele, cystic fibrosis and spinal cord injury. Additional chapters discuss choosing the right assisted conception technique and developing and managing a sperm bank. Practical and illustrative of a wide array of male fertility issues, The Diagnosis and Treatment of Male Infertility is a go-to resource for clinical andrologists, reproductive endocrinologists, urologists, primary care physicians and any professional working to treat the infertile male.