SpringerLink Springer Biomedical and Life Sciences eBooks 2017 English+International

Incluye referencias bibliográficas e índice

Analytical methods for the quantification of histamine and histamine metabolites / Heike Bähre, Volkhard Kaever -- Structural analysis of the histamine H1 receptor / Mitsunori Shiroishi, Takuya Kobayashi -- Molecular modelling approaches for the analysis of histamine receptors and their interaction with ligands / Andrea Strasser, Hans-Joachim Wittmann -- Pharmacological characterization of human histamine receptors and histamine receptor mutants in the Sf9 cell expression system / Erich H. Schneider, Roland Seifert -- Histamine release from mast cells and basophils / Francesco Borriello, Raffaella Iannone, Gianni Marone -- Histamine H2 receptor in blood cells: a suitable target for the treatment of acute myeloid leukemia / Federico Monczor, Sabrina Copsel, Natalia Fernandez, Carlos Davio, Carina Shayo -- Histamine H1 receptor gene expression and drug action of antihistamines / Hiroyuki Fukui, Hiroyuki Mizuguchi, Hisao Nemoto, Yoshiaki Kitamura, Yoshiki Kashiwada [and others] -- Histamine clearance through polyspecific transporters in the brain / Takeo Yoshikawa, Kazuhiko Yanai -- Histidine decarboxylase knockout mice as a model of the pathophysiology of Tourette Syndrome and related conditions / Christopher Pittenger -- Histamine food poisoning / Maria Schirone, Pierina Visciano, Rosanna Tofalo, Giovanna Suzzi -- Regulation of the cardiovascular system by histamine / Yuichi Hattori, Kohshi Hattori, Naoyuki Matsuda -- Changes in histidine decarboxylase, histamine N-methyltransferase and histamine receptors in neuropsychiatric disorders / Ling Shan, Ai-Min Bao, Dick F. Swaab -- Role of the histamine H3 receptor in the central nervous system / Eberhard Schlicker, Markus Kathmann -- Clinical development of histamine H4 receptor antagonists / Robin L. Thurmond, Jennifer Venable, Brad Savall, David La, Sandra Snook [and others] -- Allergy, histamine and antihistamines / Martin K. Church -- Histamine and histamine receptors in allergic dermatitis / Hiroshi Ohtsu, Masahiro Seike -- Role of the histamine H4-receptor in bronchial asthma / Detlef Neumann.

"This ​book provides a comprehensive overview on current histamine and histamine receptor research in context of human health and disease and reflect the multidisciplinary nature of the field. While the editors realize that it is almost impossible to cover the field completely within the constraints of a single HEP volume, nonetheless, all important aspects will be covered in one way or the other. An overarching introductory chapter will link the individual chapters and provide an overview on the field. This chapter will also link the book to the previous HEP volume on histamine receptors and the recent HEP volume on the pharmacology of itch. Great attention will be paid to complementation of existing literature while avoiding undue duplication. The book will cover new methods for analysis of histamine and histamine metabolites, development of methods for histamine receptor analysis, signal transduction, histamine release, regulation of immune cells by histamine, histamine metabolism and associated diseases, regulation of major organ systems by histamine and development of new drugs and experimental tools for the study of histamine receptors"--Publisher's description.