Incluye índice

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Preface; Acknowledgments; About the Editors ; Contents; Contributors; Chapter 1: Introduction; 1.1 History of the Vaginal Cytology; 1.2 History of the Vaginal Cytology in Mexico; 1.3 The Work Submitted to the Mexican Association of Gynecology and Obstetrics (1945), the References Uses Obsolete Parameters; 1.4 Chemotherapy and Concomitant Radiotherapy for Cervical Cancer; 1.5 The Sexuality of CxCa Patients; 1.6 Other Primary Tumors of the Cervix; 1.6.1 Epithelial Lineage Tumors; 1.6.2 Neuro-endocrine Tumors; 1.6.3 Mesenchymatous-Origin Tumors; 1.7 Metastatic Tumors on to the Cervix; References.

880-01 5.6 Natural History of HPV Infection; 5.7 Screening; 5.8 Nomenclature; 5.9 Approach and Treatment of Pre-invasive Lesions; 5.9.1 Colposcopic Evaluation; 5.9.2 Treatment Generalities; 5.9.3 Atypical Squamous Cells of Uncertain Significance (ASC-US) and Low-Grade Intra-epithelial Lesions; 5.9.4 High-Grade Intra-epithelial Lesion; 5.9.5 Glandular Lesions; 5.10 Treatment Options; 5.11 Conclusion; References; Chapter 6: Control and Prevention in Cervical Cancer; 6.1 Introduction; 6.2 Review of the Governmental Response in Recent Years.

3.3 Genomic Integration of HPV and Host Genomic Instability Induction as Basic Steps toward Malignant Transformation by HPV; 3.4 Telomerase Activation as Molecular Transformation and Immortalization Mechanisms by HPV; 3.5 Metabolic Tumor Adaptations as HPV Transforming Mechanisms; 3.6 Cervical Host Infections Patterns (Oncobioma) of Malignant Precursor Lesions and Tumor Microenvironment as Promoters and Enhancers of HPV Transforming Mechanisms; References; Chapter 4: Transcriptome Studies Reveal Altered Signaling Pathways in Cervical Cancer; 4.1 Introduction.

Chapter 2: Cervical Cancer Epidemiology; 2.1 Impact of Cervical Cancer (CC); 2.1.1 In the World; 2.1.2 Latin America and the Caribbean; 2.1.3 In Mexico; 2.1.3.1 Morbidity; 2.1.3.2 Mortality; 2.2 Risk Factors; 2.3 Evolution of the Cervical Cancer Program in Mexico; 2.4 The Role of the Health Care System in Mexico to Prevent Mortality and Morbidity Due to Cervical Cancer: Conclusions; References; Chapter 3: Malignant Transforming Mechanisms of Human Papillomavirus; 3.1 HPV Generalities, Life Cycle and Genome; 3.2 Transforming Mechanisms of HPV Viral Oncoproteins.

This book provides readers with a thorough review on cervical cancer, treatment guidelines and emerging therapies available for the disease. It reviews the epidemiology clinical features, diagnosis, and medical management of cervical cancer. Given the increasing need for preventive strategies, treatment optimization with collaborative and integrative work, this book improves the actual and integral knowledge in this neoplasm. Given the high prevalence of this disease in Latin America, this is an important text for clinicians in this region. This book outlines the state of the art in cervical cancer treatments and is an indispensable companion for oncologists, gynecologists, surgeons and medical students.