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Foreword; Preface; Contents; Contributors; Chapter 1: Pathophysiology of€Cirrhosis and€Portal Hypertension; Introduction; Liver Histology; Hepatocytes; Liver Sinusoidal Endothelial Cells; Kupffer Cells; Stellate Cells (Ito Cells); Outcome of€Activated Stellate Cells; Definition and€Classification of€Portal Hypertension; Intrahepatic Changes; Increased Intrahepatic Resistance; Intrahepatic Angiogenesis; Intrahepatic Microthrombosis; Extrahepatic Changes; Extrahepatic Arteriolar Vasodilation; Collateral Blood Vessel Formation; Splenomegaly and€Increased Spleen Stiffness.

Extrahepatic Imaging Manifestations Portal Hypertension and€Portosystemic Collaterals; Cavernous Transformation; Splenomegaly; Ascites; Abdominal Wall Hernia; Cholelithiasis; Bowel Wall Thickening; Hydrothorax; References; Chapter 5: Anesthesia for€Surgical Procedures in€Cirrhotic Patients Other than Liver Transplantation: Management, Concerns, and€Pitfalls; Introduction; Perioperative Risk Associated with€Liver Disease; Intraoperative Management; Monitoring and€Vascular Access; Coagulation Management; Anesthetic Technique: Neuraxial Versus General Anesthesia.

Management of€Thrombosis in€Liver DiseaseReferences; Chapter 3: The Impact of€Liver Disease on€Drug Metabolism; Hepatic Drug Clearance; Drug Metabolism; Pharmacokinetic Alterations in€Cirrhosis; Prodrug Metabolism; Liver Function Assessment and€Dosage Adjustment; Drug-Drug Interactions; Recommendations for€Select Medications in€Surgical Patients; Analgesics; Opioid Analgesics; Antiemetics; Antimicrobials; Proton Pump Inhibitors; Conclusions; References; Chapter 4: Imaging in€Cirrhotic Patients Undergoing Surgical Procedures; Introduction; Radiographic Diagnosis of€Cirrhosis.

Role of€Bacterial Translocation Role of€Portal Hypertension in€Development of€Common Complications of€Cirrhosis (Varices, Ascites, and€HRS); Esophageal Varices; Gastric and€Ectopic Varices; Portal Hypertensive Gastropathy; Ascites, Refractory Ascites and€Hepatorenal Syndrome; Diagnosis and€Measurement of€Portal Hypertension; References; Chapter 2: Coagulopathy in€Cirrhosis; Introduction; Physiology of€Normal Hemostasis; Hemostasis in€Liver Disease; Clinical Features of€Coagulopathy in€Liver Disease; Coagulation Tests in€Liver Disease; Management of€Bleeding in€Liver Disease.

Volatile Anesthetics Nitrous Oxide; Intravenous Anesthetics; Pharmacokinetic and€Pharmacodynamic Alterations; Vasopressors and€Volume Resuscitation; Transjugular Intrahepatic Portosystemic Shunt (TIPS) Procedure; Hepatic Resection; Conclusion; References; Chapter 6: Nutrition Support of€Patients with€Cirrhosis; Malnutrition and€Cirrhosis; Leading Causes of€Malnutrition in€Cirrhosis; Nutrient Metabolism; Protein Alterations; Glucose Alterations; Lipid Alterations; Other Metabolic Derangements; Nutrient Needs; Nutrition Support Indications.

This volume provides a concise yet comprehensive overview on surgical procedures performed on the cirrhotic patient. The text explains the underlying pathophysiologic alterations in liver disease and cirrhosis, provides assessment of disease severity and risk factors, and helps to predict potential outcomes based on the nature of the operation. Operations discussed in detail include bariatric surgery, colorectal surgery, hepatic surgery, kidney transplantation, gynecological procedures, neurosurgical procedures, and ophthalmic surgery. The book is also supplemented with instructive color illustrations and tables. Written by experts in the field, Surgical Procedures on the Cirrhotic Patient is a valuable, multidisciplinary resource for clinicians who treat the cirrhotic patient. With a Foreword by Thomas E. Starzl, the father of liver transplantation.

Online resource; title from PDF title page (SpringerLink, viewed May 9, 2017).