Incluye referencias bibliográficas e índice

Preface; Contents; Contributors; 1: Anatomy and€Pathogenesis of€Scleritis; Introduction; Anatomy of€the€Sclera; Vasculature; Markers of€Episcleral Vessels; Cellular Constituents of€the€Sclera; Biochemical Makeup of€the€Human Sclera; Classification of€Scleritis; Pathogenesis; Is Scleritis a€Localised Ocular Vasculitis?; Mechanisms of€Tissue Destruction in€Scleritis; Pain in€Scleritis; Animal Models of€Scleritis; Future Direction; References; 2: Essentials in€Ophthalmology, Scleritis: Classification and€Clinical Presentations of€Scleritis; Classification; Clinical Assessment.

Bacterial Scleritis Gram-Positive Coccus and€Gram-Negative Rod Scleritis [5]; Mycobacterial Scleritis; Nontuberculous Mycobacterial Scleritis; Tuberculous Mycobacterial Scleritis; Spirochetal Scleritis; Syphilitic Scleritis; Lyme Scleritis; Actinomycetic Scleritis; Nocardiosis; Fungal Scleritis; Viral Scleritis; Parasitic Scleritis; Acanthamoeba Scleritis; Toxoplasmosis Scleritis; Toxocara Scleritis; References; 5: Diagnostic Approach to€Scleritis; Introduction; Episcleritis; Anterior Scleritis; Posterior Scleritis; Etiology of€Scleritis; Noninfectious Scleritis.

Diagnosis of€Scleritis Types of€Scleritis; Complete Clinical Assessment: Aetiology and€Complications; References; 3: Associated Systemic Diseases; Introduction; Rheumatoid Arthritis; Granulomatosis with€Polyangiitis; Relapsing Polychondritis; Systemic Lupus Erythematosus; Inflammatory Bowel Disease; Polyarteritis Nodosa; Seronegative Spondyloarthropathies; References; 4: Infectious Scleritis; Introduction; Clinical Approach in€Infectious Scleritis; Investigation of€the€Illness; Diagnostic Tests; Tissue Biopsy; Therapy; Signs Aiding in€Differential Diagnosis.

Guidelines for€TherapyReferences; 8: Management with€Steroids: Local and€Systemic; Introduction; Nonsteroidal Anti-inflammatory Drugs (NSAIDs); Topical Corticosteroids; Subconjunctival Corticosteroids; Administration of€Subconjunctival Corticosteroids; Complications of€Subconjunctival Corticosteroids; Systemic Corticosteroids; Other Treatment Modalities; Complications of€Corticosteroids; References; 9: Management of€Scleritis with€Immunosuppressive Drugs and€Biologic Agents; Introduction; Systemic Corticosteroids; The Antimetabolites: Azathioprine.

Infectious Scleritis Other Causes; Investigations; References; 6: Complications and€Their Management; Introduction; Keratopathy; Peripheral Corneal Thinning; Stromal Keratitis; Peripheral Ulcerative Keratitis (PUK); Uveitis; Glaucoma; Angle-Closure Glaucoma; Open-Angle Glaucoma; Neovascular Glaucoma; Cataract; Orbital Involvement; References; 7: Management with€Nonsteroidal Anti-Ưinflammatory Agents; Introduction; Mechanism of€Action; Pharmacokinetics and€Pharmacodynamics; Efficacy; Systemic Therapy; Topical Therapy; Safety; Other Important Considerations.

This book offers a concise but comprehensive overview of scleritis, with up-to-date information on all aspects, including diagnosis and treatment. Fundamental features of the pathogenesis of scleral inflammation are first discussed as a basis for understanding the therapeutic strategies. Detailed descriptions are then provided of clinical manifestations, the complications that can arise during the course of the disease process, and the best way to manage them. An individual chapter is devoted to infectious scleritis and its management, this being an uncommon but serious condition that may result not only in loss of vision but also in loss of the globe itself. The diagnostic approach to and various management options for scleritis are then discussed extensively, with coverage of local and systemic therapy and new strategies, including biologics. Apart from the potential impact on vision, inflammation of the sclera carries a risk of association with systemic diseases, some of which can prove fatal if not promptly recognized and managed. This book is designed to allow ophthalmologists to easily identify the condition and the signs indicative of a more severe problem. It will thereby assist in safe and effective management, and help in preserving vision and life.