SpringerLink Springer Biomedical and Life Sciences eBooks 2017 English+International

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Preface -- Mutagenesis and transgenesis in zebrafish -- Developing zebrafish depression-related models -- Zebrafish models of anxiety-like behavior -- Assessing cognitive phenotypes in zebrafish -- Social phenotypes in zebrafish -- Modeling OCD endophenotypes in zebrafish -- Zebrafish models of attention-deficit/hyperactivity disorder (ADHD) -- Zebrafish neurotoxicity models -- Sleep phenotypes in zebrafish -- Zebrafish neurobehavioral assays for drug addiction research -- Zebrafish behavioral models of ageing -- Integrating morphological and behavioral phenotypes in developing zebrafish- Neuroimaging phenotypes in zebrafish -- Illustrated zebrafish neurobehavioral glossary -- Index.

Zebrafish (Danio rerio) is rapidly becoming a popular model organism in neuroscience research. The rights and wrongs of zebrafish, written by top experts in the field, summarizes the principles of behavioral neurophenotyping using this model species, and outlines the use of zebrafish to study the pathological mechanisms of neuropsychiatric disorders. The chapters discuss the use and interpretation of behavioral models to quantify emotional, cognitive, social and motor behaviors in zebrafish. This book will appeal to a wide spectrum of readership audience, from students to established investigators. The book will provide a valuable source of information for both the beginning zebrafish laboratories, and for those already actively working with zebrafish.