Incluye referencias bibliográficas

Preface; References; Contents; Contributors; 1 Epidemiology of Older Age Bipolar Disorder; 1.1 Introduction; 1.2 Definition; 1.3 Limitations; 1.4 Prevalence in the Community; 1.5 Prevalence in Treatment Settings; 1.6 Age of Onset; 1.6.1 Bimodal Distribution; 1.6.2 Cutpoints and Proportionality of Early- Versus Late-Onset Bipolar Disorder in the Treatment Population; 1.7 Demographic Distinctions; 1.8 Heterogeneous Etiologies-Including Cerebrovascular Risk Factors and Secondary Mania; 1.9 Bipolar 1 Disorder Versus Bipolar 2 Disorder; 1.10 Natural History and Course of Illness.

1.10.1 Initial Presentation1.10.2 Natural Course; 1.10.3 Increased Morbidity and Mortality; 1.10.4 Medical Comorbidity; 1.10.5 Psychiatric Comorbidity; 1.11 Summary; References; 2 Clinical Assessment of Older Adults with Bipolar Disorder; 2.1 Introduction; 2.2 Differential Diagnosis; 2.2.1 Mania and Physical Health; 2.2.2 Mania as a Symptom of Dementia; 2.2.3 Secondary Mania with a Neurological Cause; 2.2.4 Mania in the Context of Established Older Age Bipolar Disorder; 2.3 Assessment; 2.3.1 The Clinical Interview and History-Taking; 2.3.2 Risk Assessment; 2.3.3 Cognitive Assessment.

2.4 Symptom Rating Scales2.4.1 Assessment of Comorbidities; 2.4.1.1 Psychiatric Comorbidities; 2.4.1.2 Recognizing and Assessing Somatic Comorbidities; 2.5 Summary and Directions for Future Research; References; 3 Neurobiology of Older Age Bipolar Disorder; 3.1 Introduction; 3.2 White Matter Hyperintensities, Vascular Risk, and Cognitive Function; 3.3 Volumetric Differences in Particular Regions of the Brain; 3.4 Diffusion Tensor Imaging; 3.5 Magnetic Resonance Spectroscopy; 3.6 Functional Neuroimaging: PET, SPECT, and fMRI; 3.7 Bipolar Disorder as a Neuroprogressive Disorder.

3.7.1 Biomarkers of Oxidative Stress and Mitochondrial Dysfunction3.8 Clinical Implications Present and Future; 3.9 Summary and Conclusion; References; 4 Clinical Management of Older Age Bipolar Disorder; 4.1 Introduction; 4.2 Organizing Care; 4.3 Self-management, Psychoeducation, and Psychotherapy; 4.4 Drug Interactions and Tolerance; 4.5 Interactions of Drugs Frequently Used in Bipolar Disorder; 4.5.1 Lithium; 4.5.2 Valproate; 4.5.3 Carbamazepine; 4.5.4 Lamotrigine; 4.5.5 Antipsychotics; 4.6 Specific Pharmacotherapies and Electroconvulsive Therapy; 4.6.1 General Recommendations.

4.6.2 Lithium4.6.2.1 Clinical Recommendations for Lithium Therapy; 4.6.3 Anticonvulsants; 4.6.3.1 Carbamazepine; 4.6.3.2 Valproate; 4.6.3.3 Lamotrigine; 4.6.3.4 Gabapentin; 4.6.3.5 Recommendations for Anticonvulsants; 4.6.4 Antipsychotics; 4.6.4.1 Recommendations for Antipsychotics; 4.6.5 Electroconvulsive Therapy; 4.6.6 Pharmacotherapy of Bipolar Depression; 4.6.7 Maintenance Pharmacotherapy; 4.7 Summary and Recommendations for Acute Bipolar Mania, Bipolar Depression, and Maintenance Therapy; References; 5 Older Age Bipolar Disorder and Substance Use; 5.1 Introduction.

This book provides a comprehensive but practical understanding of the clinical approach to evaluating and caring for older people with bipolar disorder. Aspects of aging that impact the diagnosis, clinical course, and management of bipolar disorder are explained; in particular, attention is drawn to the implications of comorbidities and medical complexity for the psychiatric care of older individuals with the disorder. On the other hand, similarities to treatment in younger patients are also identified. The coverage includes thorough review of current research in the field. Clinical case vignettes are used throughout to highlight practical points, and each chapter includes "clinical pearls" that summarize key points for the clinician. The book closes by examining anticipated research directions and the future needs of this patient population. Bipolar Disorder in Older Age Patients will be an ideal update for the practicing community or geriatric psychiatrist working with older patients with bipolar disorder.