Current treatment options for Fuchs endothelial dystrophy / Claus Cursiefen, Albert S. Jun, editors.
Contributor(s): Cursiefen, Claus,, editor literario | Jun, Albert S.,, editor literario
Material type:
E-bookPublisher: Cham, Switzerland : Springer, 2016Description: 1 recurso en línea.ISBN: 3319430211; 9783319430218.Subject: Córnea -- Enfermedades
| Item type | Current library | Collection | Call number | Status | Date due | Barcode | Item holds | |
|---|---|---|---|---|---|---|---|---|
LIBRO-E NO PRÉSTAMO
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Madrid Digital Acceso Electrónico (UEM) | Ciencias de la Salud | RE336 .C877 2016 EB (Browse shelf(Opens below)) | Acceso electrónico | eBook.20022409 |
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Foreword; Contents; Chapter 1: Epidemiology and€Genetic Basis of€Fuchs Endothelial Corneal Dystrophy; 1.1 Introduction; 1.2 Epidemiology; 1.3 Genetic Basis of€FECD; 1.3.1 Causal Mutations; 1.3.1.1 TCF4; 1.3.1.2 AGBL1; 1.3.1.3 LOXHD1; 1.3.1.4 SLC4A11; 1.3.1.5 ZEB1; 1.3.2 FECD Loci Identified by Genetic Linkage Analysis; 1.3.3 COL8A2 Early Onset FECD; 1.4 Future Therapies; References; Chapter 2: MicroRNAs in€FECD: A€New Therapeutic Option?; 2.1 Introduction; 2.2 MicroRNAs: Biogenesis and€Function; 2.3 MicroRNAs in€Corneal Endothelial Disease; 2.3.1 miR-184; 2.3.2 miR-29.
2.4 Clinical Potential of€miRNAs in€Corneal Endothelial Disease2.4.1 Biomarkers; 2.4.2 Therapeutic Potential; 2.5 Concluding Remarks; References; Chapter 3: Clinical Phenotypes of€Fuchs Endothelial Corneal Dystrophy (FECD), Disease Progression, Differential Diagnosis, and€Medical Therapy; 3.1 When to€Talk About€Fuchs Endothelial Corneal Dystrophy (FECD): A€Short Recourse to€History; 3.2 Clinical Phenotypes of€FECD; 3.3 Interpretation of€Morphological Examinations; 3.3.1 Noncontact Specular Microscopy; 3.3.2 Pachymetry; 3.3.3 Anterior Segment OCT; 3.3.4 In Vivo Confocal Microscopy (IVCM).
3.4 Clinical Stages and Disease Progression3.5 Differential Diagnosis; 3.5.1 Posterior Polymorphous Corneal Dystrophy (PPCD); 3.5.2 Congenital Hereditary Endothelial Dystrophy (CHED); 3.5.3 X-linked Endothelial Corneal Dystrophy (XECD); 3.5.4 PEX Keratopathy; 3.5.5 Melanin Dispersion Syndrome; 3.5.6 Pseudophakic Bullous Keratopathy; 3.5.7 Pseudoguttae; 3.6 Associations with Other Diseases; 3.6.1 Association with Anterior Basement Membrane Dystrophy; 3.6.2 Association with Keratoconus; 3.6.3 Association with Myotonic Dystrophy; 3.7 Medical Therapy; 3.7.1 Symptomatic Therapy.
3.7.2 Causative Therapy3.7.2.1 Oxidative Stress; 3.7.2.2 Endoplasmic Reticulum (ER) Stress Response; 3.7.2.3 ROCK Inhibitor; 3.8 Conclusions; References; Chapter 4: Optical and Anatomic Changes in Fuchs Endothelial Dystrophy Corneas; 4.1 Introduction; 4.2 Anatomic Changes; 4.2.1 Anterior Cornea; 4.2.1.1 Epithelium; 4.2.1.2 Keratocytes and Extracellular Matrix; 4.2.1.3 Corneal Nerves and Sensation; 4.2.2 Posterior Cornea; 4.2.2.1 Descemet Membrane; 4.2.2.2 Endothelial Cells; 4.2.3 Corneal Thickness and Curvature; 4.3 Optical Changes; 4.3.1 Small-Angle Domain and High-Order Aberrations.
4.3.2 Large-Angle Domain and Intraocular Forward Scatter4.4 Association Between Anatomy and Optics; 4.5 Implication on Clinical Decision-Making and Prospect; References; Chapter 5: Evolution of Posterior Lamellar Keratoplasty: PK - DLEK - DSEK/DSAEK - DMEK - DMET; 5.1 At the Start: Who Is Going to Win the Race-Lamellar or Penetrating Keratoplasty?; 5.2 After a Long Run: Penetrating Keratoplasty Takes the Lead; 5.3 At the Curve: Posterior Lamellar Techniques Trying to Catch Up; 5.4 Before the Finish: Lamellar Techniques' Relay on the Fast Track - From DLEK to DSEK to DMEK.
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