Foreword; Preface; Contents; Contributors; About the Editors; Part I: General Concepts; Chapter 1: Pharmacology of€Sedative Drugs Used in€Out of€Operating Room Anesthesia; Introduction; Benzodiazepines; Clinical Effects; Midazolam; Diazepam; Lorazepam; Adverse Effects; Reversal; Opioids; Clinical Effects; Fentanyl; Remifentanil; Alfentanil; Sufentanil; Meperidine; Adverse Effects; Reversal; Dexmedetomidine; Systemic Effects; Pharmacokinetics; Dose; Uses; Adverse Effects; Ketamine; Systemic Effects; Pharmacokinetics; Dose; Uses; Diphenhydramine.

Basic Pharmacokinetics and€Pharmacodynamics, Variability, Blood and€Effect Site Concentrations, Context Sensitive Halftimes Planning Administration of€IV Anaesthetics and€Sedatives with€Particular Reference to€Addressing Variability in€Broad Spectrum of€Patients: From€Those Presenting for€EGD (Young and€Fit) to€Those Undergoing Cardiac Ablation Procedures (with Very Low EF); Manual and€Target Controlled Infusion (TCI) Systems with€Their Pros and€Cons; Summary; References; Part II: Patient Safety in Procedures Outside the Operating Room.

Chapter 4: Preoperative Assessment: General Principles Introduction; History- Important Aspects to€Consider; Physical Examination; Cardiovascular System; Coronary Artery Disease (CAD); Patients with€Cardiovascular Implantable Electronic Devices (CIED); Respiratory System; Hypertension; Diabetes; Preoperative Testing; Specific Tests for€Certain Patient Populations; Electrocardiogram (ECG); Cardiac Evaluation Other Than ECG; Chest X-ray; Other Pulmonary Function Evaluation; Blood Tests; Medication Instructions to€Patients; Patient Selection for€Out of€OR Procedures; References.

Chapter 5: Fasting Guidelines: Do They Need to€Be€Different? Introduction; Metabolic Consequences of€Preoperative Fasting; Psychological Consequences of€Preoperative Fasting; Current Evidence Suggests the€Following; References; Chapter 6: Organization of€a€Sedation Suite: Setting the€Standards; Introduction; Sedation Suite Locations; Patient Selection; Guidelines for€Minimum Standards for€a€Sedation Suite; Policies and€Procedures; Space; Communication; Equipment [1]; Post-anesthesia Care; Documentation; Staff Development; Unique Non-operating Room Anesthesia Locations.

Pharmacokinetics and€Dose Adverse Effects; Uses; Pharmacokinetic and€Pharmacodynamic Considerations for€Special Patient Populations; Elderly; Obese; References; Chapter 2: Pharmacology of€Anesthetic Drugs Used in€Out of€Operating Room Anesthesia; Inhaled Anesthetics; Isoflurane; Sevoflurane; Desflurane; Nitrous Oxide; Intravenous Anesthetics; Propofol; Etomidate; Ketamine; Methohexital; References; Chapter 3: Principles of€Delivery of€Sedatives and€Intravenous Anesthetics in€Out of€Operating Room Anesthesia; Introduction.

This book covers all aspects of out of operating room anesthesia and deep sedation practice. The practical aspects of anesthesia are emphasized, with particular stress on management of unanticipated adverse events. A concise, yet comprehensive description of relevant basic sciences is also included. Although the contributors are predominantly North American, essential elements of out of OR practice in countries other than the USA are incorporated. Out of Operating Room Anesthesia: A Comprehensive Review, is primarily aimed at all anesthesia providers: anesthesiologists, nurse anesthetists and residents. Specific chapters such as dental anesthesia, anesthesia for ER procedures and sedation for cosmetic procedures are a useful reference guide to physicians exposed to brief training in anesthesia during their non-anesthesia residency program.

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