1 Central nervous system control of metabolism -- 2 Glucocorticoids and metabolic control -- 3 Anti-lipidemic drugs -- 4 Genomics and metabolism -- 5 cAMP signaling -- 6 cGMP and brown adipose tissue -- 7 Inflammatory signaling and metabolism -- 8 Insulin signaling -- 9 Nuclear receptor co-factors in metabolism -- 10 Novel treatment options in diabetes -- 11 Adipose tissue stem cells -- 12 Adipokines -- 13 Immune cells and metabolism -- 14 Brown adipose tissue in humans -- 15 Diabetes and Cancer -- 16 Cancer Cell Metabolism -- 17 Incretins.

The HEP issue on Metabolic Control provides a state-of the art overview over both classical concepts and emerging areas in metabolism and associated disorders. In this context, metabolic control is highlighted at various levels of complexity ranging from transcriptional mechanisms in metabolic pathway control over metabolic communication routes in physiology and pathophysiology to current treatment modalities and options in metabolic disorders, including type 2 diabetes and obesity. Dedicated chapters by leading experts in their fields provide a concise overview over important areas in metabolic research at a molecular level, including the role of the central nervous system in metabolism, inflammation and metabolism, pancreatic hormone signaling, brown adipose tissue, and therapeutic concepts.