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Translational Toxicology : Defining a New Therapeutic Discipline / edited by Claude L Hughes, Michael D Waters

Contributor(s): SpringerLink (Online service) | Hughes, Claude L., editor literario | Waters, Michael D., editor literario
Material type: materialTypeLabelE-bookSeries: (Molecular and Integrative Toxicology, 2168-4219).Publisher: Cham : Springer International Publishing Imprint Humana Press, 2016Edition: 1st ed.Description: 1 recurso en línea (XV, 380 páginas) : 32 ilustraciones, 12 ilustraciones en color.ISBN: 9783319274492.Subject: Medicina | FarmacologíaDDC classification: 615 Online resources: Acceso a este recurso digital (usuarios Universidad Europea de Madrid)Digital Resources
Contents:
I.Introduction -- The Opportunity to Translate Developmental Toxicology into a Therapeutic Discipline -- The Role of Toxicokinetics and Toxicodynamics in Developmental and Translational Toxicology -- II.Toxicant Modes of Action and Biomarkers -- Mutational Effects -- Ligand-Mediated Toxicology: Characterization and Translational Prospects -- Effects of Environmentally Acquired Heavy Metals and Nutrients on the Epigenome and Phenotype -- Fetal Imaging and Effects of Exposures on Growth and Function -- III.Developmental Risks of Exposures and Potential Translational Toxicology Therapeutics -- Ovarian Toxicity of Environmental Contaminants: 50 Shades of Grey -- The zToxicy Effects of a Perinatal Obesogenic Environment: Maternal Obesity and Impacts on Future Generations -- The Role of Environmental Exposures in Preterm Birth -- The Impact of Environmental Stressors on DNA Methylation, Neurobehavioral Development and Chronic Physical Aggression: Prospects for Early Protective Interventions -- Coffee Health Effects from Early Fetal Development through Childhood and Adolescence.
Abstract: Bringing together a distinguished interdisciplinary team of contributors, this volume provides a comprehensive exploration of translational toxicology�a systematic approach to developing therapeutic interventions that can protect against, mitigate, or reverse the effects of exposures. In particular, the book addresses modes of action and biomarkers, developmental risks of exposures, and potential translational toxicology therapeutics. The result is a compelling application of developmental toxicology in a new therapeutic discipline that is destined to become part of standard medical practice. Translational Toxicology: Defining a New Therapeutic Discipline is an essential text for regulatory authorities, scientists, and physicians who are concerned with environmental exposures, public health, nutrition, and pharmaceutical research and development. Basic science, epidemiological, and clinical investigators will also find this book a significant resource.
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Holdings
Item type Current library Collection Call number Copy number Status Date due Barcode Item holds
LIBRO-E NO PRÉSTAMO LIBRO-E NO PRÉSTAMO Madrid Digital Acceso Electrónico (UEM) Ciencias de la Salud RA1211 .T736 2016 EB (Browse shelf(Opens below)) .i11589887 Acceso electrónico eBOOK .i11589887
Total holds: 0

I.Introduction -- The Opportunity to Translate Developmental Toxicology into a Therapeutic Discipline -- The Role of Toxicokinetics and Toxicodynamics in Developmental and Translational Toxicology -- II.Toxicant Modes of Action and Biomarkers -- Mutational Effects -- Ligand-Mediated Toxicology: Characterization and Translational Prospects -- Effects of Environmentally Acquired Heavy Metals and Nutrients on the Epigenome and Phenotype -- Fetal Imaging and Effects of Exposures on Growth and Function -- III.Developmental Risks of Exposures and Potential Translational Toxicology Therapeutics -- Ovarian Toxicity of Environmental Contaminants: 50 Shades of Grey -- The zToxicy Effects of a Perinatal Obesogenic Environment: Maternal Obesity and Impacts on Future Generations -- The Role of Environmental Exposures in Preterm Birth -- The Impact of Environmental Stressors on DNA Methylation, Neurobehavioral Development and Chronic Physical Aggression: Prospects for Early Protective Interventions -- Coffee Health Effects from Early Fetal Development through Childhood and Adolescence.

Bringing together a distinguished interdisciplinary team of contributors, this volume provides a comprehensive exploration of translational toxicology�a systematic approach to developing therapeutic interventions that can protect against, mitigate, or reverse the effects of exposures. In particular, the book addresses modes of action and biomarkers, developmental risks of exposures, and potential translational toxicology therapeutics. The result is a compelling application of developmental toxicology in a new therapeutic discipline that is destined to become part of standard medical practice. Translational Toxicology: Defining a New Therapeutic Discipline is an essential text for regulatory authorities, scientists, and physicians who are concerned with environmental exposures, public health, nutrition, and pharmaceutical research and development. Basic science, epidemiological, and clinical investigators will also find this book a significant resource.

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