Employing 'second generation' matrices -- (MA)LDI MS mass spectrometry imaging at high specificity and sensitivity -- Techniques for fingermark analysis using MALDI MS - a practical overview -- Whole/Intact Cell MALDI MS Biotyping in Mammalian Cell Analyis -- MALDI biotyping for microorganism identification in clinical microbiology -- Future applications of MALDI-TOF MS in microbiology -- MALDESI: Fundamentals, direct analysis, and MS imaging -- Microprobe MS Imaging of Live Tissues, Cells, and Bacterial Colonies using LAESI -- Efficient production of multiply charged MALDI ions -- Food Authentication by MALDI MS - MALDI-TOF MS Analysis of Fish Species -- Quantitative MALDI MS using Ionic Liquid Matrices -- Disease profiling by MALDI MS analysis of biofluids -- Ionic Liquids and other liquid matrices for sensitive MALDI MS analysis -- Coupling liquid MALDI MS to liquid chromatography.

This book covers the state-of-the-art of modern MALDI (matrix-assisted laser desorption/ionization) and its applications. New applications and improvements in the MALDI field such as biotyping, clinical diagnosis, forensic imaging, and ESI-like ion production are covered in detail. Additional topics include MS imaging, biotyping/speciation; large-scale, high-speed MS sample profiling; new methods based on �MALDI or MALDI-like sample preparations; and the advantages of MALDI MS analysis over ESI (electrospray ionization).� This is an ideal book for graduate students and researchers in the field of bioanalytical sciences. This book also: � Showcases new techniques and applications in MALDI MS � Demonstrates how MALDI is preferable to ESI � Illustrates the pros and cons associated with biomarker discovery studies in clinical proteomics and�various application areas, such as cancer proteomics.