An era of global population aging is upon us. By 2030, one in eight people will be over age 65. Since women generally live longer than men, the health and welfare of postmenopausal women will become a significant public health concern. This book offers a comprehensive review of the life changes associated with menopause, both at the dermatological and physiological level (e.g., hormonal, immunological) and at the subcellular level. It critically examines the dermatological, biological, and clinical challenges to postmenopausal health and well-being and the current and emerging therapeutic interventions. The authors advocate a holistic approach, emphasizing the need to view the menopause as a life transition with various facets rather than as a series of distinct medical conditions to be managed. Our goal is to offer a comprehensive resource to the researchers, clinicians, physicians, and helping professions whose mission is to promote the health and well-being of women around the world.