Historical perspective of Raynaud's phenomenon -- definition, nomenclature and diagnostic criteria -- Epidemiology of Raynaudâ€{u3810}henomenon -- Thermoregulation: The Normal Structure and Function of the Cutaneous Vascular System -- Pathophysiological Regulation of the Cutaneous Vascular System in Raynaudâ€{u3810}henomenon -- Primary Raynaudâ€{u3810}henomenon -- Raynaud Phenomenon In The Pediatric Age.-Secondary Raynaudâ€{u3830}henomenon -- Traumatic Vasospastic Disease -- Other Secondary Causes -- Raynaudâ€{u380D}imics -- Nailfold Capillaries.-Non-Invasive methods of assessing Raynaudâ€{u3830}henomenon -- Angiography -- Autoantibodies in Raynaudâ€{u3810}henomenon -- Systemic Vasospasm -- Clinical Outcome Measures in Raynaudâ€{u3810}henomenon -- Design and reporting of randomised controlled trials for Raynaudâ€{u3830}henomenon -- Non-drug Approaches to Treating Raynaudâ€{u3810}henomenon -- Drug Treatment of Raynaudâ€{u3810}henomenon -- Management of digital ischemia -- Surgical Management -- Practical Approaches to Treatment: Case Studies.

Raynaudâ€{u3810}henomenon: A Guide to Pathogenesis and Treatment comprehensively reviews the understanding of a disorder that continues to challenge primary care clinicians and specialists alike.Â{u2820} In the last decade, there have been important advances not only in understanding the pathophysiology of Raynaudâ€{u3810}henomenon (RP), but also in developing diagnostic methods and effective drug and non-drug therapies.Thoroughly discussing the various manifestations of RP, including childhood RP, RP secondary to connective tissue disease, and a variety of other associated disorders that include vascular perturbation that mimics RP, this title provides a wealth of new information available on normal and abnormal thermoregulation and helps physicians identify the best therapeutic approaches to treating RP.The work offers differential diagnosis options, reviews potential causes -- such as autoimmune disease, industrial trauma, drugs, and metabolic causes --Â{u086E}d provides clear recommendations for therapy.ÂŮgaging readers with case vignettes and a plethora of visual aids, Raynaudâ€{u3810}henomenon: A Guide to Pathogenesis and Treatment is a state-of-the-art, authoritative reference and invaluable contribution to the literature that will be of interest to physicians, patients, and individuals dealing with these disease processes.