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DNA Replication - Damage from Environmental Carcinogens / by Huidong Zhang.

By: Zhang, Huidong
Contributor(s): SpringerLink (Online service)
Material type: materialTypeLabelE-bookSeries: (SpringerBriefs in Biochemistry and Molecular Biology, 2211-9353; 17).Publisher: Dordrecht, Netherlands : Springer, 2015Description: 1 recurso en línea (XI, 43 páginas) : 4 ilustraciones, 1 ilustraciones en color.ISBN: 9789401772129.Subject: Ácidos nucleicos | Citología | FarmacologíaOnline resources: Acceso a este recurso digital (usuarios Universidad Europea de Madrid)Digital Resources
Contents:
DNA replication -- Disturbances of the DNA replication system -- Fate of DNA replisome upon encountering DNA damage -- External Causes for DNA Damage -- Effect of environmental carcinogens on cellular physiology -- Protocols for studies of bypass of DNA damage by DNA polymerase.
Abstract: This book reviews the main concepts concerning DNA damage due to environmental carcinogens, the effects of DNA damage on DNA replication using a single DNA polymerase or DNA replisome, and the effects of carcinogens on various cell activities. It also introduces the detailed protocols for bypassing DNA damage. As we know, various environmental carcinogens are produced as a result of industry, agriculture, chemical engineering and vehicle exhaust in our daily life. It has been reported that the environmental carcinogens can be connected to tumors and cancer, directly threatening human health. In this regard, DNA replication is highly susceptible to damage. This book provides graduate students and researchers with an overview of the effects of environmental carcinogens on DNA replication and biological activities in cells. It offers important information for research in the areas of biochemistry, cell biology, medicine, toxicology and public health.
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Holdings
Item type Current library Collection Call number Copy number Status Date due Barcode Item holds
LIBRO-E NO PRÉSTAMO LIBRO-E NO PRÉSTAMO Madrid Digital Acceso Electrónico (UEM) Ciencias de la Salud QH465.E58 Z436 2015 EB (Browse shelf(Opens below)) .i11572103 Acceso electrónico eBOOK .i11572103
Total holds: 0

DNA replication -- Disturbances of the DNA replication system -- Fate of DNA replisome upon encountering DNA damage -- External Causes for DNA Damage -- Effect of environmental carcinogens on cellular physiology -- Protocols for studies of bypass of DNA damage by DNA polymerase.

This book reviews the main concepts concerning DNA damage due to environmental carcinogens, the effects of DNA damage on DNA replication using a single DNA polymerase or DNA replisome, and the effects of carcinogens on various cell activities. It also introduces the detailed protocols for bypassing DNA damage. As we know, various environmental carcinogens are produced as a result of industry, agriculture, chemical engineering and vehicle exhaust in our daily life. It has been reported that the environmental carcinogens can be connected to tumors and cancer, directly threatening human health. In this regard, DNA replication is highly susceptible to damage. This book provides graduate students and researchers with an overview of the effects of environmental carcinogens on DNA replication and biological activities in cells. It offers important information for research in the areas of biochemistry, cell biology, medicine, toxicology and public health.

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