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Receptor Tyrosine Kinases : Family and Subfamilies / edited by Deric L. Wheeler, Yosef Yarden.

Contributor(s): Wheeler, Deric L, editor literario | Yarden, Yosef, editor literario | SpringerLink (Online service)
Material type: materialTypeLabelE-bookPublisher: Cham, Switzerland : Springer, 2015Edition: 1st ed. 2015.Description: 1 recurso en línea (XVII, 878 p.) : 100 ilustraciones, 79 ilustraciones en color.ISBN: 9783319118888.Subject: Tecnología farmacéutica | Proteínas | Citología | Farmacia | Ciencias de la vidaDDC classification: 571.6 Online resources: Acceso a este recurso digital (usuarios Universidad Europea de Madrid)Digital Resources
Contents:
Anaplastic Lymphoma Kinase (ALK) Receptor Tyrosine Kinase (RTK) Family -- The TAM Receptor Family -- DDR Receptor Tyrosine Kinase Family -- EGFR/ERBB Receptor Tyrosine Kinase Family -- Eph Receptor Tyrosine Kinase Family -- Receptor Tyrosine Kinase textbook â€{u01A9}broblast Growth Factor Receptor (FGFR) -- Insulin/IGF1 Receptors (INSR/IGF1R) Family -- MET Receptor Tyrosine Kinase Family -- MuSK Receptor Family -- The PDGFR Receptor Family -- PTK7 Receptor Tyrosine Kinase Family -- RET Receptor Tyrosine Kinase -- ROR Receptor Tyrosine Kinase Family -- ROS1 Receptor Tyrosine Kinase -- The RYK Receptor Tyrosine Kinase Subfamily -- TIE Receptor Tyrosine Kinase Family -- TRK Receptor Family -- The VEGF Family of Ligands and Receptors -- NOK Receptor Tyrosine Kinase Family.
Summary: Receptor tyrosine kinases (RTKs) play critical roles in embryogenesis, normal physiology and several diseases, and over the last decade have become the number one targets of cancer drugs. Receptor Tyrosine Kinase: Family and Subfamilies systematically covers, for the first time, the shared structural and functional features of the RTK family. Understanding the evolutionary origin of the fifty-eight RTKs, their roles in invertebrates and in humans, as well as downstream signaling pathways, is essential for fundamental research and for attempts to develop pharmacological agents able to enhance or intercept their actions. The assembly of chapters written by experts underscores commonalities and is an ideal companion volume to Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease, which refers to specific subfamilies of RTKs, along with their unique landmarks.
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Holdings
Item type Current library Collection Call number Copy number Status Date due Barcode Item holds
LIBRO-E NO PRÉSTAMO LIBRO-E NO PRÉSTAMO Madrid Digital Acceso Electrónico (UEM) Ciencias de la Salud QP606.P78 R434 2015 EB (Browse shelf(Opens below)) .i11568422 Acceso electrónico eBOOK .i11568422
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Anaplastic Lymphoma Kinase (ALK) Receptor Tyrosine Kinase (RTK) Family -- The TAM Receptor Family -- DDR Receptor Tyrosine Kinase Family -- EGFR/ERBB Receptor Tyrosine Kinase Family -- Eph Receptor Tyrosine Kinase Family -- Receptor Tyrosine Kinase textbook â€{u01A9}broblast Growth Factor Receptor (FGFR) -- Insulin/IGF1 Receptors (INSR/IGF1R) Family -- MET Receptor Tyrosine Kinase Family -- MuSK Receptor Family -- The PDGFR Receptor Family -- PTK7 Receptor Tyrosine Kinase Family -- RET Receptor Tyrosine Kinase -- ROR Receptor Tyrosine Kinase Family -- ROS1 Receptor Tyrosine Kinase -- The RYK Receptor Tyrosine Kinase Subfamily -- TIE Receptor Tyrosine Kinase Family -- TRK Receptor Family -- The VEGF Family of Ligands and Receptors -- NOK Receptor Tyrosine Kinase Family.

Receptor tyrosine kinases (RTKs) play critical roles in embryogenesis, normal physiology and several diseases, and over the last decade have become the number one targets of cancer drugs. Receptor Tyrosine Kinase: Family and Subfamilies systematically covers, for the first time, the shared structural and functional features of the RTK family. Understanding the evolutionary origin of the fifty-eight RTKs, their roles in invertebrates and in humans, as well as downstream signaling pathways, is essential for fundamental research and for attempts to develop pharmacological agents able to enhance or intercept their actions. The assembly of chapters written by experts underscores commonalities and is an ideal companion volume to Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease, which refers to specific subfamilies of RTKs, along with their unique landmarks.

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