Multiple System Atrophy / edited by Gregor K. Wenning, Alessandra Fanciulli.
Contributor(s): SpringerLink (Online service)
| Wenning, Gregor K, editor literario
| Fanciulli, Alessandra, editor literario
Material type:
E-bookPublisher: Vienna : Springer, 2014Description: 1 recurso en línea (XVI, 198 páginas) : 33 ilustraciones, 20 ilustraciones en color.ISBN: 9783709106877.Subject: Neurociencias
| Item type | Current library | Collection | Call number | Copy number | Status | Date due | Barcode | Item holds | |
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Madrid Digital Acceso Electrónico (UEM) | Ciencias de la Salud | RC394.D35 M858 2014 EB (Browse shelf(Opens below)) | .i11563527 | Acceso electrónico | eBOOK .i11563527 |
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1. Historical Review -- 2. Epidemiology -- 3. Neuropathology -- 4. Etiopathogenesis -- 5. Animal Models -- 6. Clinical Presentation -- 7. Clinical diagnostic Criteria -- 8. Natural History -- 9. Investigations -- 10. Tratment.
This textbook provides a comprehensive monography on multiple system atrophy (MSA), a rare and fatal neurodegenerative disorder that presents with autonomic failure and either parkinsonism (MSA-P) or cerebellar ataxia (MSA-C).The underlying neuropathology of MSA is characterized by striatonigral degeneration (SND), olivopontocerebellar atrophy (OPCA) and unique oligodendroglial cytoplasmic alpha-synuclein inclusions. MSA is therefore classified among the alpha-synucleinopathies such as Parkinson`s disease, pure autonomic failure and dementia with Lewy bodies. Over the last decade there have been important advances in early diagnosis, pathogenesis research and clinical trial activity. The monography will cover the entire spectrum ranging from molecular and genetic work to symptomatic and interventional therapies. The book is written for movement disorder clinicians and basic neuroscientists interested in degenerative movement disorders.
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