Introduction -- Epidemiology of Suicide -- Treatment Emergent suicidal ideation and behavior -- The predictive utility of the CSSR -- Clinical Endophenotypes and Stress-Diathesis -- Traumatic Brain Injury (TBI) and Post Traumatic Stress Disorder (PTSD) as Risk Factors for Suicidal Thoughts and Behaviors -- Genetics risk factors in Suicide -- Is Suicide Clinically Preventable? What is the Evidence? Neurologic disease as a risk factor in Suicidal Behavior -- Suicide in the second half of life: Cognition and Decision Processes -- Early Life Trauma and Suicide -- Experimental Pharmacologic Approaches for the Reduction of Suicidal Ideation and Behavior -- Psychotherapeutic Treatment Approaches for Suicidal Individuals -- Cognitive Therapy with Suicidal Patients -- Human imaging studies of suicidal behavior and its risk factors -- Using Awake Animal Imaging to Finger-Print Drugs for CNS Liability: Risk of Suicide? miRNAs Function and Dysregulation in Suicide and Depression -- Animal models of risk factors for suicidal ideation and behavior.

This book addresses the phenomenology, demographics, and neurobehavioral aspects of suicidal behavior and its risk factors, underscoring common neurobehavioral threads among different approaches which may underlie such extreme behavior. It additionally provides an overview of new approaches, such as imaging techniques to identify at-risk individuals or in response to drug treatment associated with suicidal behavior, neurodevelopmental approaches, genetic and epigenetic linkages to suicidal behavior, animal models of specific risk factors, as well as potential biomarkers being employed to help assess risk.