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Tumor-Induced Immune Suppression : mechanisms and Therapeutic Reversal / edited by Dmitry I. Gabrilovich, Arthur Andrew Hurwitz

Contributor(s): Gabrilovich, Dmitry I., editor literario | Hurwitz, Arthur Andrew, editor literario
Material type: materialTypeLabelE-bookPublisher: New York : Springer International Publishing, 2014Edition: 2nd ed.Description: 1 recurso en línea (XIV, 464 p.) : 38 ilustraciones.ISBN: 9781489980564.Subject: Tumores -- Aspectos inmunológicosDDC classification: 614.5999 Online resources: Acceso a este recurso digital (usuarios Universidad Europea de Madrid)Digital Resources Summary: Tumor-Induced Immune Suppression - Prospects and Progress in Mechanisms and Therapeutic Reversal presents a comprehensive overview of large number of different mechanisms of immune dysfunction in cancer and therapeutic approaches to their correction. This includes the number of novel mechanisms that has never before been discussed in previous monographs. The last decades were characterized by substantial progress in the understanding of the role of the immune system in tumor progression. Researchers have learned how to manipulate the immune system to generate tumor specific immune response, which raises high expectations for immunotherapy to provide breakthroughs in cancer treatment. It is increasingly clear that tumor-induced abnormalities in the immune system not only hampers natural tumor immune surveillance, but also limits the effect of cancer immunotherapy. Therefore, it is critically important to understand the mechanisms of tumor-induced immune suppression to make any progress in the field and this monograph provides these important insights.
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Holdings
Item type Current library Collection Call number Copy number Status Date due Barcode Item holds
LIBRO-E NO PRÉSTAMO LIBRO-E NO PRÉSTAMO Madrid Digital Acceso Electrónico (UEM) Ciencias de la Salud QR188.6 .T86 2014 EB (Browse shelf(Opens below)) .i11546499 Acceso electrónico eBOOK .i11546499
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Tumor-Induced Immune Suppression - Prospects and Progress in Mechanisms and Therapeutic Reversal presents a comprehensive overview of large number of different mechanisms of immune dysfunction in cancer and therapeutic approaches to their correction. This includes the number of novel mechanisms that has never before been discussed in previous monographs. The last decades were characterized by substantial progress in the understanding of the role of the immune system in tumor progression. Researchers have learned how to manipulate the immune system to generate tumor specific immune response, which raises high expectations for immunotherapy to provide breakthroughs in cancer treatment. It is increasingly clear that tumor-induced abnormalities in the immune system not only hampers natural tumor immune surveillance, but also limits the effect of cancer immunotherapy. Therefore, it is critically important to understand the mechanisms of tumor-induced immune suppression to make any progress in the field and this monograph provides these important insights.

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