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Genetic Damage in Human Spermatozoa / edited by Elisabetta Baldi, Monica Muratori

Contributor(s): Baldi, Elisabetta, editor literario | Muratori, Monica, editor literario
Material type: materialTypeLabelE-bookSeries: Advances in Experimental Medicine and Biology; 791791Publisher: New York : Springer International Publishing, 2014Description: 1 recurso en línea (XIII, 195 p.) : 22 ilustraciones, 17 ilustraciones en color.ISBN: 9781461477839.Subject: Espermatozoides | GenéticaDDC classification: 611.01816 | 599.935 Online resources: Acceso a este recurso digital (usuarios Universidad Europea de Madrid)Digital Resources
Contents:
Structure of chromatin in spermatozoa -- Genomic changes in spermatozoa of aging male -- Chromosomal aberrations and aneuploidies -- The sperm epigenome: implications for the embryo -- Paternal reprogramming of genome: transgenerational effects -- Alterations in protamination -- Sperm DNA fragmentation and base oxidation -- Iatrogenic Genetic damage -- Sperm selection: effect on sperm DNA quality -- Effect of antioxidant treatments on sperm genetic damage -- Index.
Summary: There are several types of damage that can be found in the male gamete. Genetic damage in spermatozoa can originate during spermatogenesis, or it can originate during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. This book provides a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.
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Holdings
Item type Current library Collection Call number Copy number Status Date due Barcode Item holds
LIBRO-E NO PRÉSTAMO LIBRO-E NO PRÉSTAMO Madrid Digital Acceso Electrónico (UEM) Ciencias de la Salud QP255 .G46 2014 EB (Browse shelf(Opens below)) .i11545574 Acceso electrónico eBOOK .i11545574
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Structure of chromatin in spermatozoa -- Genomic changes in spermatozoa of aging male -- Chromosomal aberrations and aneuploidies -- The sperm epigenome: implications for the embryo -- Paternal reprogramming of genome: transgenerational effects -- Alterations in protamination -- Sperm DNA fragmentation and base oxidation -- Iatrogenic Genetic damage -- Sperm selection: effect on sperm DNA quality -- Effect of antioxidant treatments on sperm genetic damage -- Index.

There are several types of damage that can be found in the male gamete. Genetic damage in spermatozoa can originate during spermatogenesis, or it can originate during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. This book provides a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.

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