Kisspeptin signaling in reproductive biology / edited by Alexander S. Kauffman, Jeremy T. Smith
Contributor(s): Kauffman, Alexander S., editor literario
| Smith, Jeremy T., editor literario
Material type: 
E-bookSeries: Advances in Experimental Medicine and Biology; 784784Publisher: New York : Springer International Publishing, 2013Description: 1 recurso en línea (XII, 514 p.) : 100 il., 58 il. col..ISBN: 9781461461999.Subject: Sistema nervioso -- DegeneraciónOnline resources: Acceso a este recurso digital (usuarios Universidad Europea de Madrid)
Summary: Kisspeptin has been shown to be both necessary and sufficient for activation of the reproductive axis, during puberty and later in adulthood. This makes kisspeptin a fundamental component of the reproductive axis. Kisspeptin has been deemed the single most potent stimulator of GnRH neurons yet known. The importance of kisspeptin has been documented in humans as well as non-human animal models, ranging from monkeys, sheep, and rodents to numerous fish species, thus signifying a highly conserved nature of its reproductive function. Importantly, kisspeptin neurons seem to mediate many of the regulatory effects of other signals, whether they are metabolic, circadian, hormonal, or stress. This places kisspeptin neurons in a unique position to be key nodal points and conduits for conveying numerous endogenous and exogenous signals to the reproductive axis
| Item type | Current library | Collection | Call number | Copy number | Status | Date due | Barcode | Item holds | |
|---|---|---|---|---|---|---|---|---|---|
LIBRO-E NO PRÉSTAMO
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Madrid Digital Acceso Electrónico (UEM) | Ciencias de la Salud | QP363 .K57 2013 EB (Browse shelf(Opens below)) | .i11544995 | Acceso electrónico | eBOOK .i11544995 |
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Kisspeptin has been shown to be both necessary and sufficient for activation of the reproductive axis, during puberty and later in adulthood. This makes kisspeptin a fundamental component of the reproductive axis. Kisspeptin has been deemed the single most potent stimulator of GnRH neurons yet known. The importance of kisspeptin has been documented in humans as well as non-human animal models, ranging from monkeys, sheep, and rodents to numerous fish species, thus signifying a highly conserved nature of its reproductive function. Importantly, kisspeptin neurons seem to mediate many of the regulatory effects of other signals, whether they are metabolic, circadian, hormonal, or stress. This places kisspeptin neurons in a unique position to be key nodal points and conduits for conveying numerous endogenous and exogenous signals to the reproductive axis
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