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The New paradigm of immunity to tuberculosis / edited by Maziar Divangahi

Contributor(s): Divangahi, Maziar, editor literario
Material type: materialTypeLabelE-bookSeries: Advances in Experimental Medicine and Biology; 783783Publisher: New York : Springer International Publishing, 2013Description: 1 recurso en línea (VI, 292 p.) : 20 il., 17 il. col..ISBN: 9781461461111.Subject: Tuberculosis | Enfermedades víricasOnline resources: Acceso a este recurso digital (usuarios Universidad Europea de Madrid)Digital Resources Summary: This book illustrates the intimate relationship between alveolar macrophages and Mycobacterium tuberculosis (M.tb.), and the former{u2019}s role in both innate and adaptive immunity against M.tb. It covers research done over the last decade. It also explores the role of macrophage death following infection with M.tb. in determining whether successful immunity is stimulated, or whether clinical disease develops; furthermore, the function of host lipid mediators in macrophage death modality are addressed. The book also illustrates how the balance between prostaglandins and lipoxins determines whether infected macrophages undergo apoptosis or necrosis, which is the ultimate factor in the outcome of infection. Finally, it is a synthesis of the authors{u2019} recent studies and the studies of others to offer a new understanding of immunity to tuberculosis
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Holdings
Item type Current library Collection Call number Copy number Status Date due Barcode Item holds
LIBRO-E NO PRÉSTAMO LIBRO-E NO PRÉSTAMO Madrid Digital Acceso Electrónico (UEM) Ciencias de la Salud QR201.T6 N49 2013 EB (Browse shelf(Opens below)) .i11544934 Acceso electrónico eBOOK .i11544934
Total holds: 0

This book illustrates the intimate relationship between alveolar macrophages and Mycobacterium tuberculosis (M.tb.), and the former{u2019}s role in both innate and adaptive immunity against M.tb. It covers research done over the last decade. It also explores the role of macrophage death following infection with M.tb. in determining whether successful immunity is stimulated, or whether clinical disease develops; furthermore, the function of host lipid mediators in macrophage death modality are addressed. The book also illustrates how the balance between prostaglandins and lipoxins determines whether infected macrophages undergo apoptosis or necrosis, which is the ultimate factor in the outcome of infection. Finally, it is a synthesis of the authors{u2019} recent studies and the studies of others to offer a new understanding of immunity to tuberculosis

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