A remarkable family -- Childhood and student years -- Letters to a special friend -- The red urine story -- Assistant professor in Uppsala -- A trip to USA in 1944-5 -- The seminal discovery of two new diseases -- Turbulent final years in Uppsala -- The "great" medical faculty -- Allm{uml}anna sjukhuset (Malm{uml}o General Hospital) -- Professor and chairman in Malm{uml}o -- Autoimmune hepatitis -- The charismatic leader -- The carcinoid syndrome -- Start of a golden Age -- Hypergammaglobulinemia. The Jewel in the Crown -- Porphyria -- Inga Marie Nilsson - Queen of hemophilia -- Carl-Bertil Laurell -- The Division of cardiology -- Endocrinology -- Hematology in Sweden and in the world -- The light comes from the east -- Visits and visitors -- Nobel symposium III -- Emeritus professor -- New activities in Stockholm -- Jan Waldenstr{uml}om, globetrotter- Macroglobulinemia - an update -- Happy emeritus years -- The final years and the legacy.

Jan Waldenstr{uml}om (1906-1996) was the leading Swedish internist of the twentieth century. The first chapter of the book presents his remarkable family including five generations of physicians. Born in Stockholm, we follow JW to medical school at Uppsala University during 1924-33. In 1934-5, he spent a year in the laboratory of Nobel Laureate Hans Fischer in Munich. In 1937, he defended a landmark thesis on acute intermittent porphyria. As "Docent" (assistant professor) in Uppsala, he discovered two new diseases in 1943. In 1944-5, he spent 7 months in the US commissioned by the Swedish Health Board. This started friendships with leading colleagues and scientists. With time, JW fostered a worldwide network of contacts and became a most influential international star. But this was just the beginning. The book follows Waldenstr{uml}om's remarkable career including his description of chronic active hepatitis as a new disease, his introduction of nuclear medicine in Sweden, his pioneering of the concept of the concept of poly- and monoclonal gammopathies, and many more highly significant achievements. His legacy is emphasized by Waldenstr{uml}om lectures, Waldenstr{uml}om Prizes, and by the International Waldenstr{uml}om's Macroglobulinemia Foundation, IWMF, and the Bing Center for Waldenstr{uml}om's macroglobulinemia at the Dana Farber Institute of Cancer Institute of the Harvard University in Boston. And now, not least, by this comprehensive biography.