AlzRastreo: accompanying Alzheimer's patients and their caregivers -- Application of Artificial Intelligence Techniques for Cancer Data Analysis in Brazil -- Blockchain trends in education: a scientometric review -- Comparison of Deployment Options for Microservices in the Cloud -- Epymodel: A user-friendly web application for visualising COVID-19 projections for Paraguay including under-reporting and vaccination -- Expert System for Software Architecture Selection -- Gamified strategies to increase motivation in middle school programming learning: A Systematic mapping -- Google Cloud Vision and its application in image processing using a Raspberry Pi -- Human Development for the Brave: Supporting the Generation of Empathy, work in Progress -- Model for the evaluation of the quality of Open Data -- Time Model for the WellProdSim Agent-based Social Simulator -- World Model for the WellProdSim Agent-based Social Simulator.

This book constitutes the refereed proceedings of the 16th Colombian Congress on Computing, CCC 2022, held in Armenia, Colombia, during October 17-21, 2022 The 12 full papers included in this book were carefully reviewed and selected from 40 submissions. They topics of this volume include software engineering and IT architecture, human-computer interaction, cybersecurity and information security, image processing and computer vision, multimedia, artificial intelligence and robotics, education and ICT, data, information and knowledge, distributed systems and large-scale computing, and formal methods in computer systems, among others.