Índice

The biology and genetics of cells and organisms -- The nature of cancer -- Tumor viruses -- Cellular oncogenes -- Growth factors, receptors, and cancer -- Cytoplasmic signaling circuitry programs many of the traits of cancer -- Tumor suppressor genes -- Prb and control of the cell cycle clock -- P53 and apoptosis: master guardian and executioner -- Eternal life : cell immortalization and tumorigenesis -- Multi-step tumorigenesis -- Maintenance of genomic integrity and the development of cancer -- Dialogue replaces monologue : heterotypic interactions and the biology of angiogenesis -- Moving out : invasion and metastasis -- Crowd control : tumor immunology and immunotherapy -- The rational treatment of cancer.