Clinical Epidemiology -- The Japanese registries of diabetic nephropathy/diabetic kidney disease -- Diabetic kidney disease and cardiovascular disease -- Possible biomarkers for diabetic kidney disease -- Blood pressure management in diabetic kidney disease -- Glycemic control and future perspectives for treatment -- Nutrition and diet therapy for DKD -- Renal structural-functional relationships at the early stage of diabetic nephropathy among types 1 and 2 diabetes - Similarity and difference -- Study at AMED collecting 600 biopsy-proven diabetic nephropathy -- Evaluation of diabetic kidney lesions -- Nephrosclerosis and diabetic kidney disease -- Pathologic aspects I. Non diabetic-renal disease (NDRD) and diabetic kidney disease (DKD) -- Experimental Animal Models of Diabetic Kidney Disease.

This book presents the latest information on the clinical-pathological features of diabetic kidney disease. The data included is based on a cohort study of biopsy-proven diabetic nephropathy patients and nephrosclerosis patients, who were observed over a long term, and on the long-term registry for diabetic nephropathy (diabetic kidney disease) in Japan. It provides a clinical-pathological axis in clinical settings, including differential pathological/clinical diagnoses of CKD in diabetic patients (e.g. the presence of "classic" diabetic nephropathy and/or nephrosclerosis and/or other primary kidney diseases). The abundant biopsy specimens with long-term medical records provide a detailed pathological and clinical description. The book also includes urine-sample data for developing and validating possible candidates for novel biomarkers for diabetic kidney disease. Many countries, including Japan, have ageing populations, in which nephrosclerosis contributes to the progression of kidney lesions in patients with diabetic kidney disease. As such, a comparison of a diabetic nephropathy cohort with nephrosclerosis is indispensable to offer better treatments. This comprehensive and informative book is an indispensible reference resource for all physicians and researchers in the field of nephrology and diabetes