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Homocysteine Metabolism in Health and Disease / edited by Govind Prasad Dubey, Krishna Misra, Rajesh K. Kesharwani, Rudra P. Ojha.

Contributor(s): Dubey, Govind Prasad., editor literario | Misra, Krishna., editor literario | Kesharwani, Rajesh K., editor literario | Ojha, Rudra P., editor literario
Material type: materialTypeLabelE-bookPublisher: Singapore : Springer International Publishing, 2022Edition: 1st edition 2022.Description: 1 recurso en línea (XX, 276 páginas).ISBN: 9789811668678.Subject: Metabolismo -- TrastornosOnline resources: Acceso a este recurso digital (usuarios Universidad Europea de Madrid)Digital Resources
Contents:
Module 1 -- Nutrition and Health -- Module 2_Disease -- Module 3_Advanced Research .
In: Springer Nature eBookSummary: This book comprehensively reviews the association of homocysteine metabolism with the etiology of various human disorders. The well-defined chapters embedded the central and peripheral effects of homocysteine metabolism intricately related with cardiovascular, neurodegenerative, metabolic, and autoimmune disorders. Further, it discusses the mechanisms of perturbance of cellular proteostasis by elevated homocysteine levels and provides a comprehensive account of pathophysiological consequences and clinical implications of homocysteine-containing proteins. The book also reviews association of genetic variants of homocysteine metabolic genes with type 2 diabetes mellitus and obesity. It also describes the molecular mechanism of hyperhomocysteinemia in the negative/feedback regulation of neural stem cell proliferation and alterations in DNA methylation. Taken together, it summarizes the mechanisms of hyper homocysteinemia-induced endothelial dysfunction and physiological functions of hydrogen sulfide as the protective agent.
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Holdings
Item type Current library Collection Call number Status Date due Barcode Item holds
LIBRO-E NO PRÉSTAMO LIBRO-E NO PRÉSTAMO Madrid Digital Acceso Electrónico (UEM) Ciencias de la Salud RC632.H65 2022 EB (Browse shelf(Opens below)) Acceso electrónico eBook.09092031
Total holds: 0

Module 1 -- Nutrition and Health -- Module 2_Disease -- Module 3_Advanced Research .

This book comprehensively reviews the association of homocysteine metabolism with the etiology of various human disorders. The well-defined chapters embedded the central and peripheral effects of homocysteine metabolism intricately related with cardiovascular, neurodegenerative, metabolic, and autoimmune disorders. Further, it discusses the mechanisms of perturbance of cellular proteostasis by elevated homocysteine levels and provides a comprehensive account of pathophysiological consequences and clinical implications of homocysteine-containing proteins. The book also reviews association of genetic variants of homocysteine metabolic genes with type 2 diabetes mellitus and obesity. It also describes the molecular mechanism of hyperhomocysteinemia in the negative/feedback regulation of neural stem cell proliferation and alterations in DNA methylation. Taken together, it summarizes the mechanisms of hyper homocysteinemia-induced endothelial dysfunction and physiological functions of hydrogen sulfide as the protective agent.

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