Introduction -- Epidemiology of Sjögren's syndrome -- The variable clinical presentation of Sjögren's syndrome -- Diagnostic and classification criteria of Sjögren's syndrome -- On the complex pathogenesis of Sjögren's syndrome: epigenetics and epithelial cells -- On the complex pathogenesis of Sjögren's syndrome: environmental factors and cells of the innate and adaptive immune system -- Juvenile Sjögren's syndrome -- Anatomy and histology of the salivary glands -- Sonoanatomy of the major salivary glands -- Imaging of Sjögren's syndrome, with special reference to ultrasound -- Towards a scientific validation of ultrasound for Sjögren's syndrome -- Ultrasonographic scoring systems - a systematic review -- Biopsy of the minor salivary glands in Sjögren's syndrome -- Biopsy of the major salivary glands in Sjögren's syndrome, with special reference to B cell proliferation.

This book answers questions about the critical role of ultrasound in the management of patients with Sjögren's syndrome. It also covers developments rheumatologists can foresee in performing a biopsy of the parotid gland. Each chapter is authored by experts on this condition, emphasizing the extent of current understanding and dealing with unanswered challenges and pitfalls. Topics such as modern imaging techniques like ultrasound and MRI and their importance are given particular focus in this book; practitioners are increasingly using imaging techniques to refine diagnosis and guide clinical management. Additionally, as a significant emerging point of interest in the field, biopsy of the major salivary glands, particularly ultrasound-guided procedures, receives extra attention within the text. The book also includes a chapter that deals with future directions and will also review the challenges patients face with unmanaged Sjögren's syndrome. Comprehensive and concise, Sjögren's Syndrome and the Salivary Glands provides a balanced overview between the chapters and ensure homogeneity of the terminology.