The Coagulative cascade -- Clinical Indications for Direct Acting Oral Anticoagulants -- Pharmacokinetic and pharmaco-dynamic of DOACDrug-drug interaction with DO-ACsDirect Oral Anticoagulant Reversal for Management of Bleeding and Emergent Surgery -- Risk stratification for and use of DOAC therapies for stroke prevention in patient with atrial fibrillationUse of DOAC in patients with kidney disease -- Anticoagulation In Elderly Patients With Atrial FibrallationThe "Obesity Paradox" And The Use Of NOAC -- Direct Oral Anticoagulation In Cancer Patients -- DOACs and Dementia in Patients with Atrial Fibrillation -- Non-Vitamin K Antagonists and Cardiac Implantable Electronic Devices -- Direct Oral Anticoagulants and Atrial Fibrillation Ablation -- DOAC therapy in patients post left atrial appendage occlusion or isolation -- Use of Direct Oral Anticoagulants after Transcatheter Aortic Valve Replacement -- Use of Direct Oral Anticoagulants after Percutaneous Coronary Intervention -- Direct oral anticoagulants and Left Ventricular Thrombosis: the evidence for a good therapeutic approach.

This book concisely covers the latest developments in the application of direct oral anticoagulants (DOACs) within cardiovascular medicine. It details the pharmacodynamics and pharmacokinetic mechanisms of DOACs and their application in treating patients with conditions ranging from coronary heart disease through kidney disease and cancer, including their perioperative management. Direct Oral Anticoagulants: From Pharmacology to Clinical Practice systematically describes the underlying mechanisms associated with DOACs and their use to treat a range of conditions and is an indispensable resource for all trainee and practicing physicians in a range of disciplines seeking a concise up-to-date resource on the topic.