1. Introduction: Biomedical Innovation and Policy in the Twenty-First Century -- 2. The Rise of Genomics and Personalized Medicine -- 3. Patient Narratives: Personalized Medicine in the Field -- 4. Alliances: Knowledge Infrastructures, and the Digitization of Precision Health -- 5. Tumor Genesis and Precision Oncology -- 6. Trends in Precision Oncology and Precision Medicine 2.0 -- 7.Personalized medicine's impact on disease -- 8. The Genome in the Clinic and Boardroom: Biomarkers, Diagnosis, Treatment, and Education -- 9. A New Set of Clinical tools for Physicians -- 10. Legislation, Reimbursement and the Regulatory Landscape -- 11. Translational personalized medicine: Molecular profiling, druggable targets, and clinical genomic medicine -- 12. The Health Economics of Personalized Precision Medicine -- 13. Moral, Societal and Ethical Issues: Claims, Consequences, and Caveats -- 14. Conclusion.

This book provides a unique perspective on the biomedical and societal implications of personalized medicine and how it helps to mitigate the healthcare crisis and rein in ever-growing expenditure. It introduces the reader to the underlying concepts at the heart of personalized medicine. An innovative second edition, this book functions as an update to the successful first edition to include new, state-of-the-art information and advancements in the fast-paced field of personalized medicine. Chapters examine pharmacogenomics, targeted therapies, individualized diagnosis and treatment, and cancer immunotherapies. The book also features an essential discussion on how the advent of genomic technologies gives clinicians the capability to predict and diagnose disease more efficiently and offers a detailed up-to-date compilation of clinical trials in cancer leading to breakthrough therapies. The book also addresses the impact of Big Data on personalized medicine and the newfound applications of digital health and artificial intelligence. A work that advocates for a patient-centered approach, Advancing Healthcare Through Personalized Medicine, Second Edition is an invaluable text for clinicians, healthcare providers, and patients.