History of Cannabis -- Cannabis Regulations -- The demand for medical cannabis education -- Pain physicians and cannabis: attitudes and beliefs -- Cannabis Terminology -- The Endocannabinoid System -- The CB1 Receptors -- The CB2 Receptors -- Endocannabinoids: Anandamide and 2-AG -- Phytocannabinoids:Tetrahydrocannabinol (THC) -- Phytocannabinoids: Cannabidiol (CBD) -- Other Phytocannabinoids -- Cannabinoids Drug interaction -- Dronabinol (Marinol) -- Nabilone (Cesamet) -- Cannabidiol (Epidiolex) -- Nabiximols (Sativex) -- Medical Cannabis Strains -- The model of a specialized cannabis clinic -- Barriers for the prescription of cannabis-based medicines -- Practical recommendations for the use of medical cannabis -- Medical Cannabis Dosing and Titration -- Patient safety considerations -- Cannabinoids and Pain: Mechanisms of action -- Cannabinoids and Pain: Clinical Evidence -- Cannabinoids and Cancer Pain -- Cannabinoids as a substitute for opioids: Basic science and Clinical evidence -- Cannabiinoids as a substitute for opioids: Suggested algorithm -- Perioperative management of patients on cannabinoids -- The Colorado Experience -- Product Safety and Quality control -- Cannabis and brain development -- Cannabis and mental health risks -- Cannabis and adolescents -- Cannabis and child development during and after pregnancy -- Cannabis impairment and Adverse events -- Vaping hazards -- Cannabis Use Disorder -- Cannabis withdrawal -- Future research.

This book presents a well-balanced view of the potential medical use of cannabinoids in pain. It comprehensively covers the current challenges with medical cannabis utilization and provides recommendations for research and future directions. Organized into nine sections, the book begins with an introduction to medical cannabis, including its history, regulations, and the general attitudes of pain physicians on cannabis. Section two explores the biological effects of marijuana via the endocannabinoid system and its complex structure of receptors and enzymes. Sections three, four, and five then delve further into pharmacology and the mechanisms of action applicable to cannabinoids in managing pain. Timely and socially conscious, section six examines the benefits of substituting opioids with cannabinoids for preoperative management. Echoing the book's well-rounded content, sections seven and eight consider the challenges with medical cannabis, including safety and quality control, brain development risks, vaping hazards, and withdrawal. The book then closes with a look at the future of cannabis in medical research. Thoroughly and equitably composed, Cannabinoids and Pain is an invaluable resource for primary care physicians, pain and palliative care physicians, and oncologists.