Part 1. Immunology, Pathophysiology and ImmunotherapyIntroduction to Immunology and Overview of the Immune System -- Immunology of Multiple sclerosis -- Pathology of Multiple sclerosis -- Antibody pathogenesis and detection method for neuronal autoantibodies -- Mechanisms and Principles of Immunotherapy.- Part 2. Multiple Sclerosis -- Natural history of MS -- Evolution of the diagnostic criteria in MS -- Epidemiology/Demographics/Environmental effects of MS -- Pediatric MS -- Treatment of MS -- Trial design -- Disease modifying treatments -- Treatment selection and Treatment discontinuation.- Part 3. Autoimmune Neurology -- Autoimmune Encephalitis -- Autoimmune Myelitis and Myelopathy -- Autoimmune Epilepsy -- Autoimmune Movement Disorders -- Autoimmune Demyelinating disease: NMOSD and anti-MOG -- Autoimmune Ophthalmologic disease -- Autoimmune Neurology in Pediatrics -- Treatment Approaches in Autoimmune Neurology. - Part 4. Other CNS inflammatory diseases -- Neurorheumatology -- Neurosarcoidosis -- Vasculitis -- Hypertrophic Pachymeningitis -- Role of infection and immunodeficiency in inflammatory disease -- Role of Oncological disease in inflammatory disease.

This book provides a clinical focus on neuroinflammatory diseases as well as a review in pathophysiology and treatment approaches. Organized into six parts, the book begins with a basic review of the immune system and concepts for learning and treating neuroimmune conditions. The next four sections cover specific subfields of neuroimmunology and autoimmune neurology - the clinical and diagnostic features of multiple sclerosis, other autoimmune conditions of the central nervous system, autoimmune conditions of the peripheral nervous system, and systemic autoimmune conditions that affect the nervous system. To conclude, Section six discusses various clinical approaches to specific presentations in neuroimmunology, including pediatric demyelinating diseases. These sections provide practical clinical information to improve the reader's knowledge in this complex field. The chapters are written by world renown authors with extensive knowledge to help provide up to date information. The full scope of autoimmune neurology is discussed, which is a unique feature of this book. Neuroimmunology serves as a resource for those in training including residents and fellows to provide clear clinical reasoning and background in a rapidly advancing field.