Creating Value Through Digital Innovation -- Third Party Venture Legitimizing Research Data Application in Healthcare Practice -- Patients' Attitudes toward Apps for Management of a Chronic Disease -- Medical Teleconsulting Applications: An Empirical Study on Elderly Peoples' Satisfaction -- Managing My Bladder Dictates My Daily Routines: A Model for Design and Adoption of mHealth in Lower Urinary Tract Symptoms Management -- Let's Get Engaged: On the Evidence of Patient Engagement Tools and Their Integration in Patient Pathways -- Pathway Supporting Health Information Systems: Interdisciplinary Goal Integration - A Review -- A Feedback Information System for Improving Hand Hygiene on a Personal and Organizational Level.-Digital Retail -- Discovering Geographical Patterns of Retailers' Locations for Successful Retail in City Centers.

This book presents the current state of research in information systems and digital transformation. Due to the global trend of digitalization and the impact of the Covid 19 pandemic, the need for innovative, high-quality research on information systems is higher than ever. In this context, the book covers a wide range of topics, such as digital innovation, business analytics, artificial intelligence, and IT strategy, which affect companies, individuals, and societies. This volume gathers the revised and peer-reviewed papers on the topic "Domain" presented at the International Conference on Information Systems, held at the University of Duisburg-Essen in 2021.