Principles of Dynamic Hypepolarized NMR -- The Design of a Hyperpolarizer -- Sample Preparation in Hyperpolarized NMR Experimentation -- Signal Sampling Strategies in Dynamic Hyperpolarized NMR -- Chemical Shift Imaging with Dynamic Hyperpolarized NMR -- Kinetic Modeling of Enzymatic Reactions in Analyzing Hyperpolarized NMR Data -- Using Hyperpolarized NMR to Understand Biochemistry from Cells to Humans -- Innovating Metabolic Biomarkers for Hyperpolarized NMR -- New Insights on Metabolic Regulation from Dynamic Hyperpolarized NMR -- Novel Views on Heart Function from Dynamic Hyperpolarized NMR -- Dynamics of Substrate Selection in Muscle Metabolism -- Index.

This is the first book in the series to focus on dynamic hyperpolarized nuclear magnetic resonance, a burgeoning topic in biophysics. The volume follows the format and style of the Handbook of Modern Biophysics series and expands on topics already discussed in previous volumes.It builds a theoretical and experimental framework for students and researchers who wish to investigate the biophysics and biomedical application of dynamic hyperpolarized NMR. All contributors are internationally recognized experts, lead the dynamic hyperpolarized NMR field, and havefirst-hand knowledge of the chapter material. In keeping with the goal and style of the Handbook in Modern Biophysics series, the book maintains a chapter structure that contains two parts: concepts and biological application. The book integrates all the chapters into a smooth, continuous discourse.Each chapter contains didactic elements that facilitate teaching, self-study, and research preparation (summary, guide to further studies, problems, problem solutions, references).