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Organ Tissue Engineering / edited by Daniel Eberli, Sang Jin Lee, Andreas Traweger

Contributor(s): Eberli, Daniel., editor literario | Lee, Sang Jin., editor literario | Traweger, Andreas., editor literario
Material type: materialTypeLabelE-bookSeries: (Tissue Engineering and Regeneration, 2731-0566); (Biomedical and Life Sciences (SpringerNature-11642)); (Reference Module Biomedical and Life Sciences (SpringerNature-43744)).Publisher: Cham : Springer International Publishing, 2021Edition: First edition 2021.Description: 1 recurso en línea : 61 ilustraciones, 55 ilustraciones a color.ISBN: 9783030442118.Subject: Medicina regenerativa | Ingeniería biomédicaOnline resources: Acceso a este recurso digital (usuarios Universidad Europea de Madrid)Digital Resources
Contents:
Brain Central Neural System -- Vison system, retina, cornea -- Olfactory system -- Craniomaxillofacial bone engineering -- Ear, Nose and Throat -- Dental, tooth -- Thymus, Lymphoid -- Oesophagus, Trachea -- Lung -- Gastro Intestinal Tract (Organoids) -- Kidney -- Bladder/Urethra -- Liver (Biomaterial, Cells) -- Endocrine Organs (Pancreas) -- Salivary grand -- Breast Tissue / Fat Tissue -- Ovary -- Penis -- Great Vessels -- Cell sheets for cardiac tissue engineering -- Heart valve Bioengineering -- Ligament -- Meniskus als muskuloskelettaler Abschnitt -- Tendons -- Skeletal system and Muscle.
Abstract: The notion of being able to engineer complete organs has inspired an entire generation of researchers. While recent years have brought significant progress in regenerative medicine and tissue engineering, the immense challenges encountered when trying to engineer an entire organ have to be acknowledged. Despite a good understanding of cell phenotypes, cellular niches and cell-to-biomaterial interactions, the formation of tissues composed of multiple cells remains highly challenging. Only a step-by-step approach will allow the future production of a living tissue construct ready for implantation and to augment organ function. In this book, expert authors present the current state of this approach. It offers a concise overview and serves as a great starting point for anyone interested in the application of tissue engineering or regenerative medicine for organ engineering. Each chapter contains a short overview including physiological and pathological changes as well as the current clinical need. The potential cell sources and suitable biomaterials for each organ type are discussed and possibilities to produce organ-like structures are illustrated. The ultimate goal is for the generated small tissues to unfold their full potential in vivo and to serve as a native tissue equivalent. By integrating and evolving, these implants will form functional tissue in-vivo. This book discusses the desired outcome by focusing on well-defined functional readouts. Each chapter addresses the status of clinical translations and closes with the discussion of current bottlenecks and an outlook for the coming years. A successful regenerative medicine approach could solve organ shortage by providing biological substitutes for clinical use - clearly, this merits a collaborative effort.
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Holdings
Item type Current library Collection Call number Status Date due Barcode Item holds
LIBRO-E NO PRÉSTAMO LIBRO-E NO PRÉSTAMO Madrid Digital Acceso Electrónico (UEM) Ciencias de la Salud R857 .T55 2021 EB (Browse shelf(Opens below)) Acceso electrónico eBook.18122234
Total holds: 0

Brain Central Neural System -- Vison system, retina, cornea -- Olfactory system -- Craniomaxillofacial bone engineering -- Ear, Nose and Throat -- Dental, tooth -- Thymus, Lymphoid -- Oesophagus, Trachea -- Lung -- Gastro Intestinal Tract (Organoids) -- Kidney -- Bladder/Urethra -- Liver (Biomaterial, Cells) -- Endocrine Organs (Pancreas) -- Salivary grand -- Breast Tissue / Fat Tissue -- Ovary -- Penis -- Great Vessels -- Cell sheets for cardiac tissue engineering -- Heart valve Bioengineering -- Ligament -- Meniskus als muskuloskelettaler Abschnitt -- Tendons -- Skeletal system and Muscle.

The notion of being able to engineer complete organs has inspired an entire generation of researchers. While recent years have brought significant progress in regenerative medicine and tissue engineering, the immense challenges encountered when trying to engineer an entire organ have to be acknowledged. Despite a good understanding of cell phenotypes, cellular niches and cell-to-biomaterial interactions, the formation of tissues composed of multiple cells remains highly challenging. Only a step-by-step approach will allow the future production of a living tissue construct ready for implantation and to augment organ function. In this book, expert authors present the current state of this approach. It offers a concise overview and serves as a great starting point for anyone interested in the application of tissue engineering or regenerative medicine for organ engineering. Each chapter contains a short overview including physiological and pathological changes as well as the current clinical need. The potential cell sources and suitable biomaterials for each organ type are discussed and possibilities to produce organ-like structures are illustrated. The ultimate goal is for the generated small tissues to unfold their full potential in vivo and to serve as a native tissue equivalent. By integrating and evolving, these implants will form functional tissue in-vivo. This book discusses the desired outcome by focusing on well-defined functional readouts. Each chapter addresses the status of clinical translations and closes with the discussion of current bottlenecks and an outlook for the coming years. A successful regenerative medicine approach could solve organ shortage by providing biological substitutes for clinical use - clearly, this merits a collaborative effort.

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