Exploration of Host Genetic Factors associated with Malaria / by Tabish Qidwai
By: Qidwai, Tabish, autor
Material type: 
E-bookSeries: (Biomedical and Life Sciences (SpringerNature-11642)); (Biomedical and Life Sciences (R0) (SpringerNature-43708)).Publisher: Singapore : Springer International Publishing, 2021Copyright date: 2021Edition: First edition 2021.Description: 1 recurso en línea (XI, 172 páginas) : 79 ilustraciones, 48 ilustraciones a color.ISBN: 9789813347618.Subject: PaludismoOnline resources: Acceso a este recurso digital (usuarios Universidad Europea de Madrid)
| Item type | Current library | Collection | Call number | Status | Date due | Barcode | Item holds | |
|---|---|---|---|---|---|---|---|---|
LIBRO-E NO PRÉSTAMO
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Madrid Digital Acceso Electrónico (UEM) | Ciencias de la Salud | RC157 2021 EB (Browse shelf(Opens below)) | Acceso electrónico | eBook.18122022 |
Browsing Madrid Digital shelves, Shelving location: Acceso Electrónico (UEM) Close shelf browser (Hides shelf browser)
| RC156 2019 EB Encyclopedia of Malaria | RC156 .M353 2017 EB Malaria : immune response to infection and vaccination | RC157 2018 EB Complement Activation in Malaria Immunity and Pathogenesis | RC157 2021 EB Exploration of Host Genetic Factors associated with Malaria | RC157 2022 EB Malaria Immunology : Targeting the Surface of Infected Erythrocytes | RC157 .H863 2015 EB Human and Mosquito Lysozymes : Old Molecules for New Approaches Against Malaria | RC159.A5 K536 2015 EB Clinical Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antimalarials |
Chapter 1. Human genetics and infectious disease -- Part 1. RBC disorders -- Chapter 2. Sickle cell gene -- Chapter 3. Alpha-Thalassemia -- Chapter 4. Beta-Thalassemia -- Chapter 5. Duffy blood group locus -- Part 2. Metabolic enzymes -- Chapter 6. Pyruvate kinase deficiency -- Chapter 7. Glucose 6-Phosphate dehydrogenase -- Part 3. Host immune response -- Chapter 8. TNF genetic polymorphisms -- Chapter 9. iNos genetic polymorphisms -- Chapter 10. Human complement receptor 1 polymorphisms -- Chapter 11. Interferonalpha receptor-1 (IFNAR1) polymorphisms -- Part 4. Cytoadherence -- Chapter 12. Intercellular adhesion molecule-1 polymorphisms -- Chapter 13. Platelet endothelial cell adhesion molecule-1 (PECAM-1) polymorphisms -- Chapter 14. Vascular cell adhesion molecule-1 (VCAM1) polymorphisms.
This book is aimed to cover the role of genetic polymorphisms in human genes related to RBC disorders, metabolic enzymes, immune response, and cytoadherence in the susceptibility/resistance to malaria caused by Plasmodium falciparum. The chapters provide current information on the balancing trait and the significance of such traits in the malaria resistance. The book covers polymorphisms in the genes of the red blood cells-sickle cell anaemia; glucose-6-phosphate dehydrogenase deficiency and thalassemia that confer protection against malaria. In addition, the book explores selection of genetic variations in the human genome as genetic control mechanism against malaria in endemic regions. It also provides a comprehensive overview of the molecular epidemiology and natural selection of alleles in the genes which are associated with malaria, and presents description of the role of human genetic polymorphisms in malaria disease risk and disease outcome.
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