Part 1.Basic Principles -- 1. The Function(s) of Sleep -- 2. Neuroanatomical and Neurochemical Bases of Vigilance States -- 3. Omics Approaches in Sleep-Wake Regulation -- 4. The Role of Glia in Sleep Regulation and Function -- 5. Sleep- and Wake-Like States in Small 1 Networks In Vivo and In Vitro -- Part 2. Optogenetics and Pharmacogenetics -- 6. Optogenetic Dissection of Sleep-Wake States In Vitro and In Vivo -- 7. Pharmacosynthetic Deconstruction of Sleep-wake Circuits in the Brain -- 8. Clinical and Experimental Human Sleep-Wake Pharmacogenetics -- Part 3. Sleep-Wake Pathologies -- 9. Clinical Sleep-Wake Disorders I: Focus on Hypersomnias and Movement Disorders During Sleep -- 10. Clinical Sleep-Wake Disorders II: Focus on Insomnia and Circadian Rhythm Sleep Disorders -- Part 4. Current and New Targets, and Therapeutic Prospects -- 11. GABA Receptors and the Pharmacology of Sleep -- 12. Advances of Melatonin-Based Therapies in the Treatment of Disturbed Sleep and Mood -- 13. Dopamine and Wakefulness: Pharmacology, Genetics, and Circuitry -- 14. Ketamine-Induced Glutamatergic Mechanisms of Sleep and Wakefulness: Insights for Developing Novel Treatments for Disturbed Sleep and Mood -- 15. Adenosine and Sleep -- Part 5. Outlook -- 16. Adenosine and Sleep -- 17. Functional Interactions Between Sleep and Circadian Rhythms in Learning and Learning Disabilities -- 18. Sleep Physiology, circadian rhythms, Waking Performance and the Development of Sleep-Wake Therapeutics.

The chapter 'Sleep Physiology, Circadian Rhythms, Waking Performance and the Development of Sleep-Wake Therapeutics' available open access under a CC BY 4.0 license at link.springer.com.