Actin Cytoskeletal Structure in Migrating Cells -- Actin Cytoskeleton Generates Mechanical Forces for Cell Migration -- Multi-scale Mechanochemical Interactions between Cell Membrane and Actin Filaments -- Actin Network Flow and Turnover are coupled in Migrating Cells -- Mechanical Strain is involved in Actin Network Reorganization -- Actin Network Dynamics is Regulated by Actomyosin Interactions -- Biophysical Interactions between Cells and Extracellular Matrix -- Cell Migration in Engineered Micro-/Nano-environments with Controlled Physical Properties -- Engineered Biomaterial for Cell Manipulation.

This book covers topics on mechanosensing, mechanotransduction, and actin cytoskeletal dynamics in cell motility. It will contribute to a better understanding of how cells functionally adapt to their mechanical environment as well as highlighting fundamental concepts for designing material niches for cell manipulation. With topics from multidisciplinary fields of the life sciences, medicine, and engineering, the book is the first of its kind, providing comprehensive, integrated coverage of innovative approaches to cell biomechanics. It provides a valuable resource for seniors and graduate students studying cell biomechanics, and is also suitable for researchers interested in the application of methods and strategies in connection with the innovative approaches discussed. Each section of the book has been supplemented with concrete examples and illustrations to facilitate understanding even for readers unfamiliar with cell biomechanics.