MARC details
| 000 -CABECERA |
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| 001 - NÚMERO DE CONTROL |
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76368 |
| 003 - IDENTIFICADOR DEL NÚMERO DE CONTROL |
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ES-MaUEC |
| 005 - FECHA Y HORA DE LA ÚLTIMA TRANSACCIÓN |
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20230207040221.0 |
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| 008 - DATOS DE LONGITUD FIJA--INFORMACIÓN GENERAL |
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100301s2006 gw | s |||| 0|eng d |
| 020 ## - NÚMERO INTERNACIONAL ESTÁNDAR DEL LIBRO |
|---|
| Número Internacional Estándar del Libro |
9783540329671 |
| 024 7# - IDENTIFICADOR DE OTROS ESTÁNDARES |
|---|
| Número estándar o código |
10.1007/3-540-32967-6 |
| Fuente del número o código |
doi |
| 040 ## - FUENTE DE LA CATALOGACIÓN |
|---|
| Centro catalogador/agencia de origen |
ES-MaUEC |
| 050 #4 - SIGNATURA TOPOGRÁFICA DE LA BIBLIOTECA DEL CONGRESO |
|---|
| Número de clasificación |
QM562 |
| Número de documento/Ítem |
.V37 2006 EB |
| 082 04 - NÚMERO DE LA CLASIFICACIÓN DECIMAL DEWEY |
|---|
| Número de clasificación |
615 |
| 100 1# - ENTRADA PRINCIPAL--NOMBRE DE PERSONA |
|---|
| Nombre de persona |
Moncada, Salvador |
| Término indicativo de función/relación |
editor literario |
| 9 (RLIN) |
6572 |
| Número de control del registro de autoridad o número normalizado |
comprobar BNE19900113959 |
| 245 04 - MENCIÓN DE TÍTULO |
|---|
| Título |
The Vascular Endothelium I |
| Mención de responsabilidad, etc. |
edited by Salvador Moncada, Annie Higgs |
| 246 3# - FORMA VARIANTE DE TÍTULO |
|---|
| Título propio/Titulo breve |
With contributions by numerous experts |
| 260 ## - PUBLICACIÓN, DISTRIBUCIÓN, ETC. |
|---|
| Lugar de publicación, distribución, etc. |
Berlin, Heidelberg |
| Nombre del editor, distribuidor, etc. |
Springer International Publishing |
| Fecha de publicación, distribución, etc. |
2006 |
| 300 ## - DESCRIPCIÓN FÍSICA |
|---|
| Extensión |
1 recurso en línea (IX, 339 p.) |
| 336 ## - TIPO DE CONTENIDO |
|---|
| Término de tipo de contenido |
Texto (visual) |
| Código de tipo de contenido |
txt |
| Fuente |
rdacontent |
| 337 ## - TIPO DE MEDIO |
|---|
| Nombre/término del tipo de medio |
electrónico |
| Código del tipo de medio |
c |
| Fuente |
rdamedia |
| 338 ## - TIPO DE SOPORTE |
|---|
| Nombre/término del tipo de soporte |
recurso electrónico |
| Código del tipo de soporte |
cr |
| Fuente |
rdacarrier |
| 490 1# - MENCIÓN DE SERIE |
|---|
| Mención de serie |
Handbook of Experimental Pharmacology |
| Número Internacional Normalizado para Publicaciones Seriadas |
0171-2004 |
| Designación de volumen o secuencia |
176/I |
| 505 0# - NOTA DE CONTENIDO CON FORMATO |
|---|
| Nota de contenido con formato |
Normal Endothelium -- Functional Ultrastructure of the Vascular Endothelium: Changes in Various Pathologies -- Development of the Endothelium -- Transport Across the Endothelium: Regulation of Endothelial Permeability -- Calcium Signalling in the Endothelium -- Eicosanoids and the Vascular Endothelium -- Nitric Oxide and the Vascular Endothelium -- Angiotensin, Bradykinin and the Endothelium -- Endothelin -- Transport Across the Endothelium: Regulation of Endothelial Permeability. |
| 520 ## - SUMARIO, ETC. |
|---|
| Sumario, etc. |
It was with great pleasure that I accepted the invitation of Springer to edit this book. My association with the vascular endothelium covers a large part of my scientific career and, as with any good long-standing relationship, it has had moments of great excitement and periods of laborious construction. It has sometimes been difficult but has never given me cause for despondency. Indeed, in the last quarter of a century, research on the vascular endothelium has been very productive and its results have contributed, arguably more than any others, to unravelling the mystery of cardiovascular disease, its origin, its development, its complications and its prevention or treatment once it has developed. I am very happy that Annie Higgs agreed to join me in this task. Over the years we have collaborated closely and, as always, she has shouldered the brunt of the work and has made sure that things get done to everybody{u2019}s satisfaction. We have also been fortunate in that the scientists who have made some of the most significant contributions in the field agreed to write chapters; as a result, we have produced two volumes which is a good representation of our knowledge in early 2006. We are, however, aware that the field has expanded beyond all expectation and that there may have been some oversight in the covering of a specific area or some aspect of it. This is compounded by the speed at which knowledge is being generated, with more than 4,100 papers concerning the endothelium published in 2005. These volumes are organised in such a way that the early chapters discuss the structure, development and function of the normal vascular endothelium. The subsequent chapters consider conditions that lead to disruption of vascular physiology, while the later chapters deal with specific pathologies and their treatment. The final chapter describes various gene-therapy strategies for the treatment of vascular pathologies. Interestingly, although this field of research can now be considered mature, it continues to generate a great deal of new information at a time when some of its fruits are having a direct impact on clinical medicine. This is clearly exemplified in the contents of most of the chapters. The concept of endothelial dysfunction, although mooted many years ago, has come to the fore and has been very useful in defining a situation which may exist long before the overt signs of vascular diseases can be identified. Although VI Preface endothelial dysfunction is likely to comprise a variety of disturbances, it is interesting that these days it is almost exclusively measured as a decrease in nitric oxide (NO)-dependent vascular dilatation, either induced by suitable pharmacological agonists or by increases in blood flow. Oxidative stress, which is associated with the genesis of endothelial dysfunction, is a loose term used to define an imbalance between the release of oxygen-derived free radicals and the anti-oxidant systems of the body. Many years ago our work established that reactive oxygen species are important in reducing the local concentrations of both prostacyclin and NO. It is now clear that free radicals also affect other homeostatic systems in the vasculature. However, many things remain to be clarified, especially the origin of oxidative stress in early disease |
| 650 #7 - PUNTO DE ACCESO ADICIONAL DE MATERIA--TÉRMINO DE MATERIA |
|---|
| Término de materia o nombre geográfico como elemento de entrada |
Fisiología humana |
| Número de control del registro de autoridad o número normalizado |
comprobar BNE19900979803 |
| Fuente del encabezamiento o término |
embne |
| 9 (RLIN) |
140024 |
| 700 1# - PUNTO DE ACCESO ADICIONAL--NOMBRE DE PERSONA |
|---|
| Nombre de persona |
Higgs, Annie |
| Término indicativo de función/relación |
editor literario |
| 9 (RLIN) |
85398 |
| Número de control del registro de autoridad o número normalizado |
Local |
| 856 40 - LOCALIZACIÓN Y ACCESO ELECTRÓNICOS |
|---|
| Identificador Uniforme del Recurso |
https://go.openathens.net/redirector/universidadeuropea.es?url=https://link.springer.com/book/10.1007/3-540-32967-6 |
| Nota pública |
Acceso a este recurso digital (usuarios Universidad Europea de Madrid) |
| 999 ## - NÚMEROS DE CONTROL DE SISTEMA (KOHA) |
|---|
| -- |
1 |
| 901 ## - ID MILLENIUM |
|---|
| Id Millenium |
i9783540329671 |
| 907 ## - TRANSACCIONES MILLENIUM |
|---|
| id bib interno millenium |
.b12819864 |
| fecha actualizac reg bib |
10-10-17 |
| fecha creacion reg bib |
01-10-14 |
| 942 ## - ELEMENTOS DE PUNTO DE ACCESO ADICIONAL (KOHA) |
|---|
| Fuente del sistema de clasificación o colocación |
Library of Congress Classification |
| Tipo de ítem Koha |
LIBRO-E NO PRÉSTAMO |
| 945 ## - ITEM MILLENIUM |
|---|
| Signatura |
QM562 .V37 2006 EB |
| Número de copia |
1 |
| Código de barras |
eBOOK |
| Agencia |
0 |
| Localización del ejemplar (ubicación) |
mae |
| Código 2 (categoría) |
- |
| Precio |
EUR0.00 |
| Mensaje (popup en cliente staff) |
- |
| Mensaje (visible en OPAC) |
- |
| Estado |
b |
| Tipo de ejemplar |
15 |
| Total de préstamos |
0 |
| Total de renovaciones |
0 |
| Préstamos del año en curso |
0 |
| Préstamos del año anterior |
0 |
| Identificador de la copia de ejemplar en Millennium |
.i11549087 |
| Fecha de creación del ejemplar |
06-04-17 |
| 988 ## - NOTA LOCAL 598 |
|---|
| Nota local 598 |
EBOOK, EBSPRINGERrevisando |
| 998 ## - FONDO MILLENIUM |
|---|
| Biblioteca |
m |
| -- |
_alco |
| -- |
_vill |
| Fecha creación |
22-07-17 |
| Tipo de registro |
m |
| Tipo de materia |
E-book |
| e |
i |
| Idioma |
eng |
| País |
gw |
| h |
4 |