MARC details
| 000 -CABECERA |
|---|
| campo de control de longitud fija |
05669nam a2200337 i 4500 |
| 001 - NÚMERO DE CONTROL |
|---|
| campo de control |
398846 |
| 003 - IDENTIFICADOR DEL NÚMERO DE CONTROL |
|---|
| campo de control |
ES-MaUEC |
| 005 - FECHA Y HORA DE LA ÚLTIMA TRANSACCIÓN |
|---|
| campo de control |
20240315144543.0 |
| 006 - CÓDIGOS DE INFORMACIÓN DE LONGITUD FIJA--CARACTERÍSTICAS DEL MATERIAL ADICIONAL |
|---|
| campo de control de longitud fija |
a|||| o|||| 00| 0 |
| 007 - CAMPO FIJO DE DESCRIPCIÓN FÍSICA--INFORMACIÓN GENERAL |
|---|
| campo de control de longitud fija |
cr nn 008mamaa |
| 008 - DATOS DE LONGITUD FIJA--INFORMACIÓN GENERAL |
|---|
| campo de control de longitud fija |
230329s2023 sz | o |||| 0|eng d |
| 020 ## - NÚMERO INTERNACIONAL ESTÁNDAR DEL LIBRO |
|---|
| Número Internacional Estándar del Libro |
9783031215476 |
| 024 7# - IDENTIFICADOR DE OTROS ESTÁNDARES |
|---|
| Número estándar o código |
10.1007/978-3-031-21547-6 |
| Fuente del número o código |
doi |
| 040 ## - FUENTE DE LA CATALOGACIÓN |
|---|
| Centro catalogador/agencia de origen |
ES-MaUEC |
| Lengua de catalogación |
spa |
| Centro/agencia transcriptor |
ES-MaUEC |
| Centro/agencia modificador |
ES-MaUEC |
| 050 #4 - SIGNATURA TOPOGRÁFICA DE LA BIBLIOTECA DEL CONGRESO |
|---|
| Número de clasificación |
QP752 .C5 |
| Número de documento/Ítem |
2023 EB |
| 245 00 - MENCIÓN DE TÍTULO |
|---|
| Título |
Cholesterol and PI(4,5)P2 in Vital Biological Functions : |
| Resto del título |
From Coexistence to Crosstalk |
| Mención de responsabilidad, etc. |
edited by Avia Rosenhouse- Dantsker |
| 250 ## - MENCIÓN DE EDICIÓN |
|---|
| Mención de edición |
1st ed. 2023 |
| 264 #1 - PRODUCCIÓN, PUBLICACIÓN, DISTRIBUCIÓN, FABRICACIÓN Y COPYRIGHT |
|---|
| Producción, publicación, distribución, fabricación y copyright |
Cham |
| Nombre del de productor, editor, distribuidor, fabricante |
Springer International Publishing |
| Fecha de producción, publicación, distribución, fabricación o copyright |
2023 |
| 300 ## - DESCRIPCIÓN FÍSICA |
|---|
| Extensión |
1 recurso en línea |
| 336 ## - TIPO DE CONTENIDO |
|---|
| Término de tipo de contenido |
texto |
| Código de tipo de contenido |
txt |
| Fuente |
rdacontent |
| 337 ## - TIPO DE MEDIO |
|---|
| Nombre/término del tipo de medio |
electrónico |
| Código del tipo de medio |
c |
| Fuente |
rdamedia |
| 338 ## - TIPO DE SOPORTE |
|---|
| Nombre/término del tipo de soporte |
recurso electrónico |
| Código del tipo de soporte |
cr |
| Fuente |
rdacarrier |
| 490 0# - MENCIÓN DE SERIE |
|---|
| Mención de serie |
Advances in Experimental Medicine and Biology |
| Número Internacional Normalizado para Publicaciones Seriadas |
2214-8019 |
| Designación de volumen o secuencia |
1422 |
| 505 0# - NOTA DE CONTENIDO CON FORMATO |
|---|
| Nota de contenido con formato |
Preface -- 1. Mutual influence of cholesterol and PI(4,5)P2 on their levels -- Chapter 1. Mechanism of the regulation of plasma cholesterol levels by PI(4,5)P2 -- Chapter 2. Effect of cholesterol depletion on ciliary PI(4,5)P2 levels -- Chapter 3. Impact of cholesterol on PI(4,5)P2 levels in the brain -- Chapter 4. Alterations in PIP2 levels in the intracellular cholesterol trafficking disorder NPC1 -- Chapter 5. Targeting cholesterol release and PI(4,5)P2 redistribution by the oral drug Miltefosine -- 2. Cross-talk between cholesterol and PI(4,5)P2 as a factor affecting protein function -- A. Plasma membrane ion channels -- Chapter 6. From cross-talk to synergism: the combined effect of cholesterol and PI(4,5)P2 on inwardly rectifying potassium channels -- Chapter 7. Link between lysosomal cholesterol and PI(4,5)P2 in the regulation of the voltage gated KCNQ2/3 potassium channel -- Chapter 8. Cholesterol and PI(4,5)P2 binding to a ciliary membrane transient receptor potential channel -- Chapter 9. Regulation of ell by cholesterol and PI(4,5)P2 -- Chapter 10. Cholesterol stimulates the epithelial sodium channel in a PI(4,5)P2-dependent manner -- Chapter 11. Roles of cholesterol and PI(4,5)P2 in store operated calcium entry -- Chapter 12. Roles of cholesterol and PI(4,5)P2 levels in the modulation of the calcium activated chloride channel TMEM16A -- B. Lipid transport proteins--Chapter 13. PI(4,5)P2 facilitates ORP1-mediated cholesterol transport by promoting membrane targeting and cholesterol extraction -- Chapter 14. Role of PI(4,5)P2 binding in ORP2-mediated cholesterol distribution -- Chapter 15. PI(4,5)P2-dependent transport of cholesterol from lysosomes to peroxisomes at lysosomeperoxisome contact sites -- 3. Cellular processes at the intersection of cholesterol and PI(4,5)P2 involvement -- Chapter 16. The insertion of the N-terminal domain of Gasdermin-D is increased by PI(4,5)P2 and decreased by cholesterol -- Chapter 17. Cholesterol promotes the cooperative interaction of formins with PI(4,5)P2 to initiate actin nucleation -- Chapter 18. Cooperation between cholesterol and PI(4,5)P2 in the regulation of Engrailed-2 homeoprotein intercellular trafficking -- Chapter 19. Cholesterol and PI(4,5)P2 as a membrane nanoplatform for HIV assembly -- Chapter 20. Role of Cholesterol and PI(4,5)P2 in the localization of the HIV-1 structural polyprotein Gag to the plasma membrane. |
| 520 ## - SUMARIO, ETC. |
|---|
| Sumario, etc. |
Cholesterol is an essential component of the plasma membrane. Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2), although a minor phospholipid, is the most abundant membrane phosphoinositide. Both lipids play key roles in a variety of cellular functions including as signalling molecules and major regulators of protein function. Studies on these important lipids have traditionally focused on the effect of each lipid individually. Accumulating evidence indicates, however, that these lipids may cross-regulate each other's levels. Furthermore, it is becoming evident that cholesterol and PI(4,5)P2 can act together to modulate protein function and biological processes. This book provides an overview of cellular functions and molecular mechanisms in which cholesterol and PI(4,5)P2 functions extend from parallel existence to crosstalk. It includes four sections. The first section introduces the reader to cholesterol and PI(4,5)P2. The second section demonstrates the mutual influence of these two critical lipids on their levels. The third section, divided into two parts, describes the co-modulation of protein function by cholesterol and PI(4,5)P2. The first part focuses on ion channels and the second - on lipid transfer proteins. The fourth section highlights other cellular processes at the intersection of cholesterol and PI(4,5)P2 involvement. Collectively, the book portrays the emerging relationship between cholesterol and PI(4,5)P2 in a broad array of biological systems and processes. The book will be of interest to a wide audience of research scientists with an interest in the biophysical properties of lipids and the physiological consequences of their presence in biological systems, as well as graduate students, postdoctoral trainees, basic and clinical researchers, and pharmaceutical scientists. Specifically, the content will be relevant to researchers in the fields of biochemistry, molecular biophysics, pharmacology, neurobiology, cardiovascular biology, among others. |
| 988 ## - NOTA LOCAL 598 |
|---|
| Nota local 598 (boletines) |
Springer_BiomedLife_2023 |
| 650 #7 - PUNTO DE ACCESO ADICIONAL DE MATERIA--TÉRMINO DE MATERIA |
|---|
| Fuente del encabezamiento o término |
embne |
| 9 (RLIN) |
139711 |
| Término de materia o nombre geográfico como elemento de entrada |
Colesterol |
| 856 40 - LOCALIZACIÓN Y ACCESO ELECTRÓNICOS |
|---|
| Identificador Uniforme del Recurso |
https://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-031-21547-6 |
| Nota pública |
Acceso a este recurso digital (usuarios Universidad Europea de Madrid) |
| 942 ## - ELEMENTOS DE PUNTO DE ACCESO ADICIONAL (KOHA) |
|---|
| Fuente del sistema de clasificación o colocación |
Library of Congress Classification |
| Tipo de ítem Koha |
LIBRO-E NO PRÉSTAMO |
| 998 ## - DATOS ESTADÍSTICOS |
|---|
| Fecha de catalogación |
|
| Tipo de materia |
E-book |
| Catalogador |
Isabel Alonso |
| Catalogado |
Sí |