Ex vivo engineering of the tumor microenvironment
Ex vivo engineering of the tumor microenvironment
Amir R. Aref, David Barbie, editors
- 1 recurso en línea
- Cancer drug discovery and development .
SpringerLink
Incluye referencias bibliográficas
1. Introduction to Ex Vivo Cancer Models -- 2. Patient-derived Xenografts in Oncology -- 3.Organoid Culture: Applications in Development and Cancer -- 4. Microfluidics and future of cancer diagnostics -- 5. Advancing techniques and insights in circulating tumor cell (CTC) research -- 6. The Cancer Secretome -- 7. An overview of the tumor microenvironments and future of cancer therapy.
This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time.
3319453955 3319453971 9783319453958 9783319453972
Cáncer--Aspectos genéticos
RC268.4 / 2017 EB
SpringerLink
Incluye referencias bibliográficas
1. Introduction to Ex Vivo Cancer Models -- 2. Patient-derived Xenografts in Oncology -- 3.Organoid Culture: Applications in Development and Cancer -- 4. Microfluidics and future of cancer diagnostics -- 5. Advancing techniques and insights in circulating tumor cell (CTC) research -- 6. The Cancer Secretome -- 7. An overview of the tumor microenvironments and future of cancer therapy.
This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time.
3319453955 3319453971 9783319453958 9783319453972
Cáncer--Aspectos genéticos
RC268.4 / 2017 EB