Plasma Cell Dyscrasias
Plasma Cell Dyscrasias
edited by Aldo M Roccaro, Irene M Ghobrial
- Cham Springer International Publishing 2016
- 1 recurso en línea (VI, 361 páginas) 9 ilustraciones, 7 ilustraciones en color
- Cancer Treatment and Research 169 0927-3042 .
MGUS and smoldering myeloma -- Multiple Myeloma -- Primary amyloidosis, systemic light chain and heavy chain diseases plasmacytoma -- Waldenstrom�s Macroglobulinemia.
This book provides a concise overview of the state of the art in the biology and treatment of plasma cell malignancies, a heterogeneous group of diseases primarily characterized by the presence of clonal plasma cells within the bone marrow or extramedullary sites. The plasma cell dyscrasias investigated include monoclonal gammopathy of undetermined significance (MGUS), multiple myeloma, plasmacytoma, immunoglobulin deposition diseases (primary amyloidosis and systemic light and heavy chain deposition diseases), and Waldenström�s macroglobulinemia. In the case of multiple myeloma, the coverage ranges from genomic aberrations and microRNAs to treatment for different patient groups, upcoming novel therapies, immunotherapy, and transplantation. The book reflects the significant research advances achieved in this field during the past few years, which have enhanced our understanding of the molecular mechanisms responsible for the pathogenesis of plasma cell dyscrasias.
9783319403205
Medicina
Biología molecular
RC280.B6 / 2016 EB
616.15
MGUS and smoldering myeloma -- Multiple Myeloma -- Primary amyloidosis, systemic light chain and heavy chain diseases plasmacytoma -- Waldenstrom�s Macroglobulinemia.
This book provides a concise overview of the state of the art in the biology and treatment of plasma cell malignancies, a heterogeneous group of diseases primarily characterized by the presence of clonal plasma cells within the bone marrow or extramedullary sites. The plasma cell dyscrasias investigated include monoclonal gammopathy of undetermined significance (MGUS), multiple myeloma, plasmacytoma, immunoglobulin deposition diseases (primary amyloidosis and systemic light and heavy chain deposition diseases), and Waldenström�s macroglobulinemia. In the case of multiple myeloma, the coverage ranges from genomic aberrations and microRNAs to treatment for different patient groups, upcoming novel therapies, immunotherapy, and transplantation. The book reflects the significant research advances achieved in this field during the past few years, which have enhanced our understanding of the molecular mechanisms responsible for the pathogenesis of plasma cell dyscrasias.
9783319403205
Medicina
Biología molecular
RC280.B6 / 2016 EB
616.15