Pan-cancer Integrative Molecular Portrait Towards a New Paradigm in Precision Medicine

Pan-cancer Integrative Molecular Portrait Towards a New Paradigm in Precision Medicine edited by Christophe Le Tourneau, Maud Kamal - 1st ed. - Cham, Switzerland Springer 2015 - 1 recurso en línea (X, 144 p.) 100 il., 50 il. col.

This original book provides readers with an overview of the latest developments in personalized medicine clinical trials in oncology. The topics covered range from the rationale behind this new generation of clinical trials and the latest statistical models for high-throughput molecular techniques, bioinformatics, high-throughput screening molecular techniques and the challenges entailed by implementing them in daily practice. It also covers the key role of pathology in the validation of molecular results and the complex assessment of predictive biomarkers. The different topics covered are supplemented by unique concrete examples based on the SHIVA trial. The authors are all members of the French Curie Institute, one of the worldâ€oremost cancer research institutions.

9783319221892


Ensayos clínicos

R853.C55 / 2015 EB

616.994