Scorpion Venoms

Scorpion Venoms edited by P. Gopalakrishnakone, Lourival D. Possani, Elisabeth F. Schwartz, Ricardo C. RodräAz de la Vega. - Dordrecht, Netherlands Springer 2015 - 1 recurso en línea (115 ilustraciones, 92 ilustraciones en color eReference. - Toxinology 4 .

Scorpions have fascinated humans for a long time, èi» and foremost because of the harm the sting of a few species could cause but also due to their unique natural history and for the many biologically active compounds found in their venoms. This volume of the Toxinology handbook series covers all those aspects. The subjects are divided into seven sections starting with an introduction to the general aspects of scorpion biology and ecology, followed by the description of the ãaȶenvenomationãaÈthophysiology, pharmacokinetics, and pharmacodynamics of venoms and their complex interactions with the immune system. The future of anti-scorpion venom therapy is then covered in two chapters dedicated to alternatives to the century-old techniques currently used to produce ãaȶanti-venomsãaÈhe next section presents a world tour of ãaȶscorpionismãaÈd dangerous scorpion species and their impact on human health. It is worth remembering that envenomation due to scorpion stings is a substantial health hazard in Asian, Middle Eastern, African, and Latin American countries, with over one million people stung by scorpions every year, resulting in more than 3,000 deaths. Species-centered overviews of ãaȶscorpion venomsãaÈe presented in the next section, after which a section details the two main types of ãaȶscorpion toxinsãaÈhe last section covers high-throughput transcriptome and proteome screenings now known as ãaȶvenomicsãaÈis volume provides chapters that are accessible to a broad audience, yet also contains the depth of knowledge and detail which makes it of interest to experts in the field. Readers of this reference work will leave well informed on the current state of the art of scorpion venom research.

9789400764040

10.1007/978-94-007-6404-0 doi


Tecnología farmacéutica
Fisiología animal
Farmacología

RA1255 / .S367 2015