Inflammation and Immunity in Cancer
Inflammation and Immunity in Cancer
edited by Tsukasa Seya, Misako Matsumoto, Keiko Udaka, Noriyuki Sato.
- Tokyo Springer 2015
- 1 recurso en línea (XI, 268 páginas) 72 ilustraciones, 60 ilustraciones en color
Preface -- 1 Role of bone marrow-derived CCR1+ cells in colon cancer invasion and metastasis.-ÂGE2-associated inflammation and gastrointestinal tumorigenesis -- 3Âulation of tumor-associated myeloid cells by innate immune signaling -- 4 The role of PIKfyve in TLR-mediated inflammation and immune responses -- 5 Emerging roles of an innate immune regulator TAPE in the Toll-like receptor and RIG-I-like receptor pathways -- 6 Anchorage-dependent multicellular aggregate formation induces CD44 high cancer stem cell-like phenotypes in adult T-cell leukemia/lymphoma cells -- 7Âor-associated molecular patterns: its implication in tumoricidal inflammation -- 8Âst factors involved in the propagation and pathogenesis of hepatitis C virus.-ÂHCV-induced inflammation: The role of cross-talk between HCV-infected hepatocytes and stellate cells -- 10Âvelopment of immunotherapy for hepatocellular carcinoma -- 11Âvelopment of glypican-3-targeted cancer immunotherapy -- 12Â vesicular traffic system in plasmacytoid dendritic cells as a target for immune regulation -- 13Â vivo targeting of dendritic cells with artificial adjuvant vector cells (aAVC) as a novel cancer immunotherapy -- 14Âhancement of efficacy of WT1 peptide cancer vaccine by co-administration with immunopotentiating agents: Lessons from mouse models -- 15Âulation of antigen-presentation by dendritic cells and its application to cancer immunotherapy -- 16Ânew mode of CTL induction secondary to alteration of pMHCI repertoire by antigen processing defects -- 17Âgress in clinical use of CCR4 antibody for regulatory T cell suppression -- 18 Adjuvant Immunotherapy for cancer: Basic research to clinical bench -- 19 Immunological regulation of human cancer stem cell/cancer-initiating cells (CSC/CIC) -- 20Âerview on tumor immunology.-BM Epilogue.
This book overviews cancer immunity from broad scientific fields, based on the concept that cancer is a sort of by-product of infection, inflammation, and host immune response. The innate and acquired arms of the immune system mainly participate in tumor immune surveillance, and their activation is critically modulated by the situation of the tumor microenvironment. Many types of immune cells join the formation of the microenvironment. In particular, macrophages and dendritic cells enter the tumor mass to be main players in the inflammatory milieu of tumors. After introducing these topics, the book discusses immunotherapy for cancer patients as an outgrowth of this concept of infection and inflammation. With the contributions of leading scientists actively involved in the field of antitumor immunity study, this book encourages readers to understand the mechanism of general cancers based on inflammation and will facilitate prevention and the development of therapeutics for cancer.
9784431553274
10.1007/978-4-431-55327-4 doi
Inmunología
Inmunología
RC268.3 / I545 2015
Preface -- 1 Role of bone marrow-derived CCR1+ cells in colon cancer invasion and metastasis.-ÂGE2-associated inflammation and gastrointestinal tumorigenesis -- 3Âulation of tumor-associated myeloid cells by innate immune signaling -- 4 The role of PIKfyve in TLR-mediated inflammation and immune responses -- 5 Emerging roles of an innate immune regulator TAPE in the Toll-like receptor and RIG-I-like receptor pathways -- 6 Anchorage-dependent multicellular aggregate formation induces CD44 high cancer stem cell-like phenotypes in adult T-cell leukemia/lymphoma cells -- 7Âor-associated molecular patterns: its implication in tumoricidal inflammation -- 8Âst factors involved in the propagation and pathogenesis of hepatitis C virus.-ÂHCV-induced inflammation: The role of cross-talk between HCV-infected hepatocytes and stellate cells -- 10Âvelopment of immunotherapy for hepatocellular carcinoma -- 11Âvelopment of glypican-3-targeted cancer immunotherapy -- 12Â vesicular traffic system in plasmacytoid dendritic cells as a target for immune regulation -- 13Â vivo targeting of dendritic cells with artificial adjuvant vector cells (aAVC) as a novel cancer immunotherapy -- 14Âhancement of efficacy of WT1 peptide cancer vaccine by co-administration with immunopotentiating agents: Lessons from mouse models -- 15Âulation of antigen-presentation by dendritic cells and its application to cancer immunotherapy -- 16Ânew mode of CTL induction secondary to alteration of pMHCI repertoire by antigen processing defects -- 17Âgress in clinical use of CCR4 antibody for regulatory T cell suppression -- 18 Adjuvant Immunotherapy for cancer: Basic research to clinical bench -- 19 Immunological regulation of human cancer stem cell/cancer-initiating cells (CSC/CIC) -- 20Âerview on tumor immunology.-BM Epilogue.
This book overviews cancer immunity from broad scientific fields, based on the concept that cancer is a sort of by-product of infection, inflammation, and host immune response. The innate and acquired arms of the immune system mainly participate in tumor immune surveillance, and their activation is critically modulated by the situation of the tumor microenvironment. Many types of immune cells join the formation of the microenvironment. In particular, macrophages and dendritic cells enter the tumor mass to be main players in the inflammatory milieu of tumors. After introducing these topics, the book discusses immunotherapy for cancer patients as an outgrowth of this concept of infection and inflammation. With the contributions of leading scientists actively involved in the field of antitumor immunity study, this book encourages readers to understand the mechanism of general cancers based on inflammation and will facilitate prevention and the development of therapeutics for cancer.
9784431553274
10.1007/978-4-431-55327-4 doi
Inmunología
Inmunología
RC268.3 / I545 2015