RNA and DNA Diagnostics

RNA and DNA Diagnostics edited by Volker A. Erdmann, Stefan Jurga, Jan Barciszewski. - Cham, Switzerland Springer 2015 - 1 recurso en línea (X, 349 páginas) 124 ilustraciones, 78 ilustraciones en color - RNA Technologies 2197-9731 .

Electrochemical Biosensors for miRNA Detection -- Electrochemical Detection of RNA.-ÂA and PNA probes for DNA Detection in Electroanalytical Systems -- DNA for Non-Nucleic Acid Sensing -- Aptamers in Oncotherapy -- Genotyping of Single Nucleotide Polymorphism -- Environmentally Responsive and Bright Fluorescent Probes Possessing Dansyl-modified Oligonucleotides under Hybridization of DNA and RNA -- Fluorescent Nucleic Acid Analogues in Research and Clinical Diagnostics -- Emergent Properties and Functions of Nanoconfined Nucleic Acid Architectures -- RNA and DNA Diagnostics on Microspheres: Current and Emerging Methods -- DNA and RNA Electronic Properties for Molecular Modifications and Environmental State Diagnostics -- Mechanochemical Sensing.-Âcroarrays as Research Tools and Diagnostic Devices -- Quadruplex Priming Amplification (QPA) for Nucleic Acid Diagnostics.-Âgle-molecule strategies for DNA and RNA diagnostics -- Detection and Assessment of microRNA Expression in Human Disease.

The aim of molecular diagnostics is preferentially to detect a developing disease before any symptoms appear. There has been a significant increase, fueled by technologies from the human genome project, in the availability of nucleic acid sequence information for all living organisms including bacteria and viruses. When combined with a different type of instrumentation applied, the resulting diagnostics is specific and sensitive. Nucleic acid-based medical diagnosis detects specific DNAs or RNAs from the infecting organism or virus and a specific gene or the expression of a gene associated with a disease. Nucleic acid approaches also stimulate a basic science by opening lines of inquiry that will lead to greater understanding of the molecules at the center of life. One can follow Richard Feynmanâ€amous statement “What I cannot create, I do not understand.â€

9783319173054

10.1007/978-3-319-17305-4 doi


Biología molecular
Biotecnología
Genética humana

QP623 / .R533 2015