Synthetic Biology : From iGEM to the Artificial Cell

Porcar, Manuel

Synthetic Biology : From iGEM to the Artificial Cell by Manuel Porcar, Juli Peretó - Dordrecht, Netherlands Springer 2014 - 1 recurso en línea (XII, 77 p.) 24 ilustraciones, 21 ilustraciones col. - SpringerBriefs in Biochemistry and Molecular Biology 12 2211-9353 . - SpringerBriefs in Biochemistry and Molecular Biology 12 .

Synthetic Biology (SB) is a revolutionary discipline with a vast range of practical applications, but is SB research really based on engineering principles? Does it contributing to the artificial synthesis of life or does it utilise approaches sufficiently advanced to fall outside the scope of biotechnology or metabolic engineering? This volume reviews the development of SB and includes the major milestones of the discipline, the â€t̃op-downâ€d â€b̃ottom-upâ€proaches towards the construction of an artificial cell and the development of the “iGEMâ€mpetition. We conclude that SB is an emerging field with extraordinary technological potential, but that most research projects actually are an extension of metabolic engineering since the complexity of living organisms, their tight dependence on evolution and our limited knowledge of the interactions between the molecules, actually make life difficult to engineer.

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Bioingeniería

TA164 / .P673 2014 EB