Evolution-adjusted Tumor Pathophysiology: : The Novel Language of Tumor Biology
Reichle, Albrecht.
Evolution-adjusted Tumor Pathophysiology: : The Novel Language of Tumor Biology edited by Albrecht Reichle. - Dordrecht, Netherlands Springer International Publishing 2013 - 1 recurso en línea (X, 453 p.) 95 ilustraciones, 87 ilustraciones en color
Preface.-IÂtroduction.-Communication âvolution âathophysiology: An endogenous conjunction âstead of an introduction.-II Combined modularized therapies for metastatic tumors: Pointing to centralÂblems of communication among â€s̃ystems participators†tumors -- Applied systems biology for the control of metastatic cancer: Therapeutic top-down strategy for targeting the tumorsâ€rmativity -- Targeting the proangiogenic network in angiosarcomas: Biomodulatory therapy.-Âng-term results of combined modularized, immune-modulatory, angiostatic, and antiinflammatory therapy in systemically pre-treated multi-systems Langerhans cell histiocytosis.-Âirecting and modulating rationalizations of tumor-immanent normative functions in castration-resistant prostate ancer.-III Social engineering: Biomodulation, either endogenously initiated or by implementation of non-normative boundary conditions -- Non-hierarchically organized operations in malignancies: Stromal dysfunction induces hematopoetic malignancies.-Âomodulatory therapy approaches in renal clear cell carcinoma: A perspective.-Âteome analysis identified the PPARc ligand 15d-PGJ2 as a novel drug inhibiting melanoma progression and interfering with tumor-stroma interaction.IV The tumorsâ€rmativity: Reconstructing and operationalizing startingÂpoints for an evolution theory.- philosophical quest of a cancer cell: Redefining existentialism.- tumorâ€ormativity: Normative structures, action norms and decision maxims as therapeutic targets for tumor therapy.-Âiticizable claims for the validity of communication acts in biological systems: Therapeutic implications in cancer.-VÂolution theory.-Âolution theory: Its practical relevance for understanding tumorÂelopment and specifying tumor therapy -- Modularity, subjectivity, intersubjectivity and normativity: Clinically applicable operative benchmarks -- Turning upside down the mode of science to emphasize and harness the impact of environmental communicative events. From genome- or organ-centric to rationalization-centric systematization ofÂors -- Purposive-rational tumor therapy: Exploiting the tumor l̃iving worldâ€or diversifying, specifying and personalizing tumor therapy -- Including rationalizations of tumor-associated normative notions inÂhophysiologic considerations: Communication-theoretical implications.-VIIÂReconstruction of tumor-immanent normative functions, structures and decision maxims (hubs).-Âidging a diagnostic and therapeutic gap: Selecting, assessing and categorizing tumor-associated normative notions.-Âsonalizing tumor pathophysiology by diagnosing developmental problems in tumors with imaging techniques -- Biologic memory: Induction by metronomically administered combined modularized therapy.-ÂI tool of rationalizations constituting tumor-associated normativeÂions: non-genomic counterpart of the tumor genome and therefore,Âimportant therapeutic target for diversifying palliative care -- Diversifying and specifying palliative care for patients with metastatic cancer by therapeutic implementation of non-normative boundary conditions -- Targeting a hallmark of cancer: Simultaneous inflammation and tumor control for palliative care in metastatic cancer.-IXÂvel clinical and pharmaceutical technology for bioengineering tumorÂponse.-Âmbined modularized tumor therapy âumor biology ând prognostic factors: Bioengineering tumor response.-X Objectifying the systems objectsâ€bjectivity in biological systems: A novel reification of the scientific picture about the â€õbjectiveâ€rld -- The systems objectsâ€bjectivity as scientific object. Index.
Combined modularized therapies for metastatic cancer are pointing to central problems of communication among â€s̃ystems participators†communication theory explains 'social engineering', endogenously induced or by implementing non-normative boundary conditions. Evolution-adjusted tumor pathophysiology is borne by an evolution theory, which contrasts narrative evolution histories. The tool of rationalizations constituting the tumor's normativity (inflammation, immune response etc.) represents the non-genomic counterpart of the tumor genome and should be additionally assessed during tumor staging. Evolution-adjusted tumor pathophysiology allows implementing applied systems biology, a novel clinical and pharmaceutical technology for bioengineering tumor response and personalizing tumor therapy. Combined modularized therapy, evolution-adjusted tumor pathophysiology, and â€ũniversalâ€omarkers concertedly address genetically based tumor heterogeneity.
9789400768666
10.1007/978-94-007-6866-6 doi
Tecnología farmacéutica
RC254.6 / R453 2013
Evolution-adjusted Tumor Pathophysiology: : The Novel Language of Tumor Biology edited by Albrecht Reichle. - Dordrecht, Netherlands Springer International Publishing 2013 - 1 recurso en línea (X, 453 p.) 95 ilustraciones, 87 ilustraciones en color
Preface.-IÂtroduction.-Communication âvolution âathophysiology: An endogenous conjunction âstead of an introduction.-II Combined modularized therapies for metastatic tumors: Pointing to centralÂblems of communication among â€s̃ystems participators†tumors -- Applied systems biology for the control of metastatic cancer: Therapeutic top-down strategy for targeting the tumorsâ€rmativity -- Targeting the proangiogenic network in angiosarcomas: Biomodulatory therapy.-Âng-term results of combined modularized, immune-modulatory, angiostatic, and antiinflammatory therapy in systemically pre-treated multi-systems Langerhans cell histiocytosis.-Âirecting and modulating rationalizations of tumor-immanent normative functions in castration-resistant prostate ancer.-III Social engineering: Biomodulation, either endogenously initiated or by implementation of non-normative boundary conditions -- Non-hierarchically organized operations in malignancies: Stromal dysfunction induces hematopoetic malignancies.-Âomodulatory therapy approaches in renal clear cell carcinoma: A perspective.-Âteome analysis identified the PPARc ligand 15d-PGJ2 as a novel drug inhibiting melanoma progression and interfering with tumor-stroma interaction.IV The tumorsâ€rmativity: Reconstructing and operationalizing startingÂpoints for an evolution theory.- philosophical quest of a cancer cell: Redefining existentialism.- tumorâ€ormativity: Normative structures, action norms and decision maxims as therapeutic targets for tumor therapy.-Âiticizable claims for the validity of communication acts in biological systems: Therapeutic implications in cancer.-VÂolution theory.-Âolution theory: Its practical relevance for understanding tumorÂelopment and specifying tumor therapy -- Modularity, subjectivity, intersubjectivity and normativity: Clinically applicable operative benchmarks -- Turning upside down the mode of science to emphasize and harness the impact of environmental communicative events. From genome- or organ-centric to rationalization-centric systematization ofÂors -- Purposive-rational tumor therapy: Exploiting the tumor l̃iving worldâ€or diversifying, specifying and personalizing tumor therapy -- Including rationalizations of tumor-associated normative notions inÂhophysiologic considerations: Communication-theoretical implications.-VIIÂReconstruction of tumor-immanent normative functions, structures and decision maxims (hubs).-Âidging a diagnostic and therapeutic gap: Selecting, assessing and categorizing tumor-associated normative notions.-Âsonalizing tumor pathophysiology by diagnosing developmental problems in tumors with imaging techniques -- Biologic memory: Induction by metronomically administered combined modularized therapy.-ÂI tool of rationalizations constituting tumor-associated normativeÂions: non-genomic counterpart of the tumor genome and therefore,Âimportant therapeutic target for diversifying palliative care -- Diversifying and specifying palliative care for patients with metastatic cancer by therapeutic implementation of non-normative boundary conditions -- Targeting a hallmark of cancer: Simultaneous inflammation and tumor control for palliative care in metastatic cancer.-IXÂvel clinical and pharmaceutical technology for bioengineering tumorÂponse.-Âmbined modularized tumor therapy âumor biology ând prognostic factors: Bioengineering tumor response.-X Objectifying the systems objectsâ€bjectivity in biological systems: A novel reification of the scientific picture about the â€õbjectiveâ€rld -- The systems objectsâ€bjectivity as scientific object. Index.
Combined modularized therapies for metastatic cancer are pointing to central problems of communication among â€s̃ystems participators†communication theory explains 'social engineering', endogenously induced or by implementing non-normative boundary conditions. Evolution-adjusted tumor pathophysiology is borne by an evolution theory, which contrasts narrative evolution histories. The tool of rationalizations constituting the tumor's normativity (inflammation, immune response etc.) represents the non-genomic counterpart of the tumor genome and should be additionally assessed during tumor staging. Evolution-adjusted tumor pathophysiology allows implementing applied systems biology, a novel clinical and pharmaceutical technology for bioengineering tumor response and personalizing tumor therapy. Combined modularized therapy, evolution-adjusted tumor pathophysiology, and â€ũniversalâ€omarkers concertedly address genetically based tumor heterogeneity.
9789400768666
10.1007/978-94-007-6866-6 doi
Tecnología farmacéutica
RC254.6 / R453 2013