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Pharmacotherapy of Pulmonary Hypertension edited by Marc Humbert, Oleg V. Evgenov, Johannes-Peter Stasch - 1 recurso en línea (IX, 576 p.) 66 ilustraciones, 56 ilustraciones en color - Handbook of Experimental Pharmacology 218 0171-2004 .

Preface.- Part I. Pulmonary hypertension: conceptual bases of the disease. Pulmonary hypertension: definition, classification, and epidemiology. Pulmonary hypertension: pathophysiology and signalling pathways. Pulmonary hypertension: pathology. Pulmonary hypertension: biomarkers. Pulmonary hypertension: animal models -- Part II. Pulmonary hypertension: established therapies. General supportive care. Calcium channel blockers. Prostacyclins. Endothelin receptor antagonists. Phosphodiesterase 5 inhibitors -- Part III. Pulmonary hypertension: novel pathways and emerging therapies Soluble guanylate cyclase stimulators. Therapeutics targeting dysregulated redox equilibrium and endothelial dysfunction (NOXs, sGC activators, GSNOR). Rho-kinase inhibitors. Serotonin transporters and serotonin receptors. PDGF inhibitors. Novel anti-proliferative strategies beyond imatinib. Immunosuppressive agents. Vasoactive peptides. Inhibitors of cGMP/cAMP metabolism (MRP4, MRP5, PDE1). Old targets re-visited. Stem cells and cell based therapy -- Part IV. Conclusions and Outlook. Pulmonary hypertension: evidence-based management in the modern era and future directions

ISBN: 9783642386640

Standard No.: 10.1007/978-3-642-38664-0 doi

Subjects--Topical Terms:
Farmacología respiratoria

LC Class. No.: RM388 / .P43 2013 EB

Dewey Class. No.: 615